侵袭性肺炎球菌病（IPD）再现，新冠疫情防控措施放宽后血清型 23B 增加，瑞士，2021 年。
Re-emergence of invasive pneumococcal disease (IPD) and increase of serotype 23B after easing of COVID-19 measures, Switzerland, 2021.
机构信息
Swiss National Reference Center for Invasive Pneumococci (NZPn), Institute for Infectious Diseases, University of Bern, Bern, Switzerland.
Institute for Infectious Diseases, University of Bern, Bern, Switzerland.
出版信息
Emerg Microbes Infect. 2021 Dec;10(1):2202-2204. doi: 10.1080/22221751.2021.2000892.
Incidence of invasive pneumococcal disease (IPD) has been low during the peak of the COVID-19 pandemic. In this study, we found that the IPD numbers again increased in Switzerland during the first six months of 2021 and that this coincides with the loosening of COVID-19 measures. Vaccine pneumococcal serotypes have continued to decrease and non-vaccine type serotype 23B has emerged (8% of the isolates in 2021). Worryingly, serotype 23B is associated with reduced susceptibility to penicillin.
在 COVID-19 大流行高峰期，侵袭性肺炎球菌病（IPD）的发病率一直较低。在这项研究中，我们发现 2021 年前六个月瑞士的 IPD 病例数再次增加，这与 COVID-19 措施的放宽相吻合。疫苗肺炎球菌血清型持续减少，而非疫苗型血清型 23B 出现（2021 年的分离株占 8%）。令人担忧的是，血清型 23B 与青霉素敏感性降低有关。
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