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肝脏移植中的黏弹性监测。

Viscoelastic Monitoring in Liver Transplantation.

机构信息

Department of Liver Anesthesia and Critical CareInstitute of Liver Diseases and Transplantation Gleneagles Global Health City Chennai India Department of Hepatobiliary Surgery and Liver TransplantationInstitute of Liver Diseases and Transplantation Gleneagles Global Health City Chennai India.

出版信息

Liver Transpl. 2022 Jun;28(6):1090-1102. doi: 10.1002/lt.26352. Epub 2021 Dec 3.

Abstract

Cirrhosis and liver transplantation (LT) surgery are associated with substantial alterations to the patient's coagulation status. Accurate monitoring of these changes during LT can help manage bleeding proactively and potentially reduce transfusion requirements. Unlike conventional coagulation tests (CCTs), viscoelastic monitoring (VEM) can provide an accurate, real-time, point-of-care assessment of coagulation status during LT and hence has become an invaluable tool for anesthetists and intensive care physicians. However, it remains an enigmatic subject for transplantation surgeons who are more conversant with CCTs. This review discusses the principles of VEM, provides a primer to understanding and interpreting its output, and explains how it can be used to make real-world clinical decisions during LT.

摘要

肝硬化和肝移植 (LT) 手术会导致患者的凝血状态发生重大变化。在 LT 期间准确监测这些变化有助于主动管理出血并可能减少输血需求。与传统的凝血检测 (CCT) 不同,黏弹性监测 (VEM) 可以在 LT 期间提供准确、实时、即时的凝血状态评估,因此已成为麻醉师和重症监护医生不可或缺的工具。然而,对于更熟悉 CCT 的移植外科医生来说,它仍然是一个神秘的课题。这篇综述讨论了 VEM 的原理,提供了理解和解释其输出的基础知识,并解释了如何在 LT 期间使用它来做出实际的临床决策。

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