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儿童内镜逆行胰胆管造影术中透视时间延长的预测因素:大型儿童内镜逆行胰胆管造影数据库倡议多中心队列研究结果

Predictors of Prolonged Fluoroscopy Exposure in Pediatric Endoscopic Retrograde Cholangiopancreatography: Results From the Large Pediatric Endoscopic Retrograde Cholangiopancreatography Database Initiative Multicenter Cohort.

作者信息

Liu Quin Y, Ruan Wenly, Fishman Douglas S, Barth Bradley A, Tsai Cynthia Man-Wai, Giefer Matthew J, Kim Kyung Mo, Martinez Mercedes, Dall'Oglio Luigi, De Angelis Paola, Torroni Filippo, Faraci Simona, Bitton Sam, Wilsey Michael, Khalaf Racha T, Werlin Steven, Dua Kulwinder, Huang Clifton, Gugig Roberto, Mamula Petar, Fox Victor L, Grover Amit S, Quiros J Antonio, Zheng Yuhua, Troendle David M

机构信息

Cedars-Sinai Medical Center; David Geffen School of Medicine at UCLA, Los Angeles, CA.

Baylor College of Medicine; Texas Children's Hospital, Houston, TX.

出版信息

J Pediatr Gastroenterol Nutr. 2022 Mar 1;74(3):408-412. doi: 10.1097/MPG.0000000000003347.

Abstract

BACKGROUND AND AIMS

Ionizing radiation exposure during endoscopic retrograde cholangiopancreatography (ERCP) is an important quality issue especially in children. We aim to identify factors associated with extended fluoroscopy time (FT) in children undergoing ERCP.

METHODS

ERCP on children <18 years from 15 centers were entered prospectively into a REDCap database from May 2014 until May 2018. Data were retrospectively evaluated for outcome and quality measures. A univariate and step-wise linear regression analysis was performed to identify factors associated with increased FT.

RESULTS

1073 ERCPs performed in 816 unique patients met inclusion criteria. Median age was 12.2 years (interquartile range [IQR] 9.3-15.8). 767 (71%) patients had native papillae. The median FT was 120 seconds (IQR 60-240). Factors associated with increased FT included procedures performed on patients with chronic pancreatitis, ERCPs with American Society of Gastrointestinal Endoscopy (ASGE) difficulty grade >3, ERCPs performed by pediatric gastroenterologist (GI) with adult GI supervision, and ERCPs performed at non-free standing children's hospitals. Hispanic ethnicity was the only factor associated with lower FT.

CONCLUSION

Several factors were associated with prolonged FTs in pediatric ERCP that differed from adult studies. This underscores that adult quality indicators cannot always be translated to pediatric patients. This data can better identify children with higher risk for radiation exposure and improve quality outcomes during pediatric ERCP.

摘要

背景与目的

内镜逆行胰胆管造影术(ERCP)期间的电离辐射暴露是一个重要的质量问题,在儿童中尤为如此。我们旨在确定接受ERCP的儿童中与延长透视时间(FT)相关的因素。

方法

2014年5月至2018年5月期间,来自15个中心的18岁以下儿童的ERCP前瞻性地录入到一个REDCap数据库中。对数据进行回顾性评估以获取结果和质量指标。进行单变量和逐步线性回归分析以确定与FT增加相关的因素。

结果

816例独特患者中进行的1073例ERCP符合纳入标准。中位年龄为12.2岁(四分位间距[IQR]9.3 - 15.8)。767例(71%)患者有天然乳头。中位FT为120秒(IQR 60 - 240)。与FT增加相关的因素包括对慢性胰腺炎患者进行的操作;美国胃肠内镜学会(ASGE)难度等级>3的ERCP;在成人胃肠病学家监督下由儿科胃肠病学家(GI)进行的ERCP;以及在非独立儿童医院进行的ERCP。西班牙裔种族是与较低FT相关的唯一因素。

结论

儿科ERCP中几个因素与较长的FT相关,这与成人研究不同。这强调了成人质量指标不能总是适用于儿科患者。这些数据可以更好地识别辐射暴露风险较高的儿童,并改善儿科ERCP期间的质量结果。

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