儿科 ERCP 在急性胰腺炎治疗中的应用：一项国际多中心队列研究的二次分析。
Pediatric ERCP in the Setting of Acute Pancreatitis: A Secondary Analysis of an International Multicenter Cohort Study.
机构信息
From Johns Hopkins All Children's Hospital, St. Petersburg, FL.
University of South Florida Morsani College of Medicine, Tampa, FL.
出版信息
J Pediatr Gastroenterol Nutr. 2023 Jun 1;76(6):817-821. doi: 10.1097/MPG.0000000000003762. Epub 2023 Mar 12.
Previous studies have demonstrated the safety of performing endoscopic retrograde cholangiopancreatography (ERCP) in the pediatric population; however, few have addressed the outcomes of children undergoing ERCP during acute pancreatitis (AP). We hypothesize that ERCP performed in the setting of AP can be executed with similar technical success and adverse event profiles to those in pediatric patients without pancreatitis. Using the Pediatric ERCP Database Initiative, a multi-national and multi-institutional prospectively collected dataset, we analyzed 1124 ERCPs. One hundred and ninety-four (17%) of these procedures were performed in the setting of AP. There were no difference in the procedure success rate, procedure time, cannulation time, fluoroscopy time, or American Society of Anesthesiology class despite patients with AP having higher American Society of Gastrointestinal Endoscopy grading difficulty scores. This study suggests that ERCP can be safely and efficiently performed in pediatric patients with AP when appropriately indicated.
先前的研究已经证实了在儿科人群中进行内镜逆行胰胆管造影（ERCP）的安全性；然而，很少有研究涉及在急性胰腺炎（AP）期间接受 ERCP 的儿童的结果。我们假设，在 AP 情况下进行的 ERCP 可以具有与无胰腺炎的儿科患者相似的技术成功率和不良事件谱。使用儿科 ERCP 数据库倡议，一个多国家和多机构前瞻性收集的数据集，我们分析了 1124 例 ERCP。其中 194 例（17%）在 AP 情况下进行。尽管 AP 患者的美国胃肠内镜学会（ASGE）分级难度评分较高，但在手术成功率、手术时间、插管时间、透视时间或美国麻醉师协会（ASA）分级方面，两组之间没有差异。本研究表明，在适当的情况下，ERCP 可以安全有效地用于患有 AP 的儿科患者。
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