Dyson D C, Miller P D, Armstrong M A
Am J Obstet Gynecol. 1987 Apr;156(4):928-34. doi: 10.1016/0002-9378(87)90359-0.
Three hundred two low-risk obstetric patients with an unfavorable cervical examination and well-established gestational age of at least 287 days were randomly selected for management by either antepartum fetal testing or prostaglandin gel cervical ripening followed by aggressive induction of labor and delivery. The patients managed by induction of labor had a lower incidence of meconium-stained amniotic fluid, meconium aspiration, low Apgar scores, postmaturity syndrome, fetal distress, and cesarean delivery than did patients managed with antepartum fetal testing. Our data suggest that prostaglandin gel cervical ripening and induction of labor and delivery by 42 weeks' gestation may be the most appropriate management for patients with well-established gestational age and an unfavorable cervical examination.
302例宫颈检查结果不利且孕周至少已达287天的低风险产科患者被随机选择，分别接受产前胎儿检测或前列腺素凝胶宫颈成熟治疗，随后积极引产和分娩。与接受产前胎儿检测的患者相比，接受引产治疗的患者羊水粪染、胎粪吸入、阿氏评分低、过熟综合征、胎儿窘迫及剖宫产的发生率更低。我们的数据表明，对于孕周明确且宫颈检查结果不利的患者，妊娠42周时使用前列腺素凝胶宫颈成熟并引产分娩可能是最合适的处理方式。
