Takada Shunya, Tsunoda Akira, Takahashi Tomoko, Kusanagi Hiroshi
Department of Gastroenterological Surgery, Kameda Medical Center, Kamogawa, Japan.
Ann Coloproctol. 2022 Aug;38(4):290-296. doi: 10.3393/ac.2020.00920.0131. Epub 2021 Nov 2.
Aluminum potassium sulfate and tannic acid (ALTA; Zion, Mitsubishi Pharma Corp.) is an effective sclerosing agent for internal hemorrhoids. ALTA therapy with a rectal mucopexy (AM) is a new approach for treating hemorrhoidal prolapse. This study compared the early postoperative outcomes of AM surgery with Doppler-guided transanal hemorrhoidal dearterialization and mucopexy (DM) in patients with third-degree hemorrhoids.
AM surgery was performed on 32 patients with grade III hemorrhoids and was compared with a cohort of 22 patients who underwent DM surgery in a previous randomized controlled trial.
The pain scores during defecation were significantly lower in the AM patients beginning 4 days after surgery. The total use of analgesics 2 weeks postoperatively was significantly lower in the AM patients than in the DM patients (3.5 tablets [range 1.6-5.5] vs. 7.6 tablets [range 3.3-11.9], P=0.04). The length of operation, blood loss, and incidence of postoperative complications were significantly lower in the AM patients than in the DM patients. During 12 months follow-up, recurrence of prolapse occurred in 1 patient who underwent AM surgery.
AM surgery is effective, with lower complication rates and postoperative analgesic requirements, and is a less invasive treatment for patients with grade III hemorrhoids compared to DM surgery.
硫酸铝钾和鞣酸(ALTA;Zion,三菱制药公司)是一种有效的内痔硬化剂。ALTA联合直肠黏膜固定术(AM)是治疗痔脱垂的一种新方法。本研究比较了III度痔患者行AM手术与多普勒引导下经肛门痔动脉结扎及黏膜固定术(DM)的术后早期结果。
对32例III度痔患者进行AM手术,并与之前一项随机对照试验中22例行DM手术的患者队列进行比较。
AM组患者术后4天开始排便时的疼痛评分显著更低。AM组患者术后2周的镇痛药总用量显著低于DM组患者(3.5片[范围1.6 - 5.5] vs. 7.6片[范围3.3 - 11.9],P = 0.04)。AM组患者的手术时间、失血量和术后并发症发生率显著低于DM组患者。在12个月的随访期间,1例行AM手术的患者出现脱垂复发。
与DM手术相比,AM手术有效,并发症发生率更低,术后镇痛需求更少,是III度痔患者的一种侵入性较小的治疗方法。