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一种使用硫酸铝钾和鞣酸硬化疗法联合黏膜固定术治疗Ⅲ度痔疮患者的新型非切除技术的术后早期结果。

Early postoperative outcomes of a novel nonexcisional technique using aluminum potassium sulfate and tannic acid sclerotherapy with mucopexy on patients with grade III hemorrhoids.

作者信息

Takada Shunya, Tsunoda Akira, Takahashi Tomoko, Kusanagi Hiroshi

机构信息

Department of Gastroenterological Surgery, Kameda Medical Center, Kamogawa, Japan.

出版信息

Ann Coloproctol. 2022 Aug;38(4):290-296. doi: 10.3393/ac.2020.00920.0131. Epub 2021 Nov 2.

DOI:10.3393/ac.2020.00920.0131
PMID:34724727
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9441537/
Abstract

PURPOSE

Aluminum potassium sulfate and tannic acid (ALTA; Zion, Mitsubishi Pharma Corp.) is an effective sclerosing agent for internal hemorrhoids. ALTA therapy with a rectal mucopexy (AM) is a new approach for treating hemorrhoidal prolapse. This study compared the early postoperative outcomes of AM surgery with Doppler-guided transanal hemorrhoidal dearterialization and mucopexy (DM) in patients with third-degree hemorrhoids.

METHODS

AM surgery was performed on 32 patients with grade III hemorrhoids and was compared with a cohort of 22 patients who underwent DM surgery in a previous randomized controlled trial.

RESULTS

The pain scores during defecation were significantly lower in the AM patients beginning 4 days after surgery. The total use of analgesics 2 weeks postoperatively was significantly lower in the AM patients than in the DM patients (3.5 tablets [range 1.6-5.5] vs. 7.6 tablets [range 3.3-11.9], P=0.04). The length of operation, blood loss, and incidence of postoperative complications were significantly lower in the AM patients than in the DM patients. During 12 months follow-up, recurrence of prolapse occurred in 1 patient who underwent AM surgery.

CONCLUSION

AM surgery is effective, with lower complication rates and postoperative analgesic requirements, and is a less invasive treatment for patients with grade III hemorrhoids compared to DM surgery.

摘要

目的

硫酸铝钾和鞣酸(ALTA;Zion,三菱制药公司)是一种有效的内痔硬化剂。ALTA联合直肠黏膜固定术(AM)是治疗痔脱垂的一种新方法。本研究比较了III度痔患者行AM手术与多普勒引导下经肛门痔动脉结扎及黏膜固定术(DM)的术后早期结果。

方法

对32例III度痔患者进行AM手术,并与之前一项随机对照试验中22例行DM手术的患者队列进行比较。

结果

AM组患者术后4天开始排便时的疼痛评分显著更低。AM组患者术后2周的镇痛药总用量显著低于DM组患者(3.5片[范围1.6 - 5.5] vs. 7.6片[范围3.3 - 11.9],P = 0.04)。AM组患者的手术时间、失血量和术后并发症发生率显著低于DM组患者。在12个月的随访期间,1例行AM手术的患者出现脱垂复发。

结论

与DM手术相比,AM手术有效,并发症发生率更低,术后镇痛需求更少,是III度痔患者的一种侵入性较小的治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd16/9441537/9d7166354b0a/ac-2020-00920-0131f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd16/9441537/214a0c89f0c3/ac-2020-00920-0131f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd16/9441537/ad39634b7c35/ac-2020-00920-0131f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd16/9441537/cf6626d24b24/ac-2020-00920-0131f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd16/9441537/9d7166354b0a/ac-2020-00920-0131f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd16/9441537/214a0c89f0c3/ac-2020-00920-0131f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd16/9441537/ad39634b7c35/ac-2020-00920-0131f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd16/9441537/cf6626d24b24/ac-2020-00920-0131f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd16/9441537/9d7166354b0a/ac-2020-00920-0131f4.jpg

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