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新型非切除技术联合明矾钾硫酸和鞣酸硬化剂黏膜固定术治疗 III 度痔的中期疗效。

Mid-term outcome of a novel nonexcisional technique using aluminum potassium sulfate and tannic acid sclerotherapy with mucopexy on patients with grade III hemorrhoids.

机构信息

Department of Gastroenterological Surgery, Kameda Medical Center, Kamogawa City, Chiba, Japan.

出版信息

Tech Coloproctol. 2023 Dec;27(12):1335-1343. doi: 10.1007/s10151-023-02863-6. Epub 2023 Oct 17.

DOI:10.1007/s10151-023-02863-6
PMID:37848640
Abstract

BACKGROUND

Aluminum potassium sulfate and tannic acid (ALTA) is an effective sclerosing agent for the treatment of internal hemorrhoids. ALTA therapy with rectal mucopexy (AM) is a new approach for treating hemorrhoidal prolapse. This study investigated the midterm outcomes of AM surgery in patients with hemorrhoids.

METHODS

Patients with grade III hemorrhoids who underwent AM surgery were enrolled in this retrospective analysis of prospectively collected data from a single institution. Cumulative success rates, postoperative symptoms, including pain scores, analgesic requirements, and postoperative complications, and patient satisfaction were assessed.

RESULTS

The median number of ALTA injection procedures was 3 (range 1-4), and the median total injection dose was 19 mL (range 7-32 mL). The median number of mucopexy procedures was 2 (range 1-4). The median postoperative pain score (0 = no pain at all, 10 = worst pain imaginable) at rest or during defecation were ≤2. The total dose of analgesics administered during the first two weeks after surgery was 1 (range 0-25). Six patients (5.3%) showed postoperative complications: five showed Clavien-Dindo (C-D) grade I and one showed C-D grade IIIa complications. Cumulative success rates at one, three, and five years were 96.5%, 85.3%, and 85.3%, respectively. Patient satisfaction scores, which were assessed using a 10-point scale, were ≥9 at each postoperative year.

CONCLUSIONS

AM surgery is an effective non-excisional surgery with satisfactory mid-term results for grade III hemorrhoids, and is associated with lower complication rates, postoperative analgesic requirements, and higher patient satisfaction.

摘要

背景

硫酸铝钾和鞣酸(ALTA)是治疗内痔的有效硬化剂。直肠黏膜固定术(AM)联合 ALTA 治疗痔脱垂是一种新的治疗方法。本研究旨在探讨 AM 手术治疗痔脱垂的中期疗效。

方法

本回顾性研究分析了单中心前瞻性收集的资料,纳入了接受 AM 手术的 III 度痔患者。评估了累积成功率、术后症状(包括疼痛评分、镇痛需求和术后并发症)以及患者满意度。

结果

ALTA 注射次数中位数为 3 次(范围 1-4 次),总注射剂量中位数为 19 mL(范围 7-32 mL)。黏膜固定术中位数为 2 次(范围 1-4 次)。术后休息或排便时的中位数疼痛评分(0 分为完全无痛,10 分为想象中最痛的疼痛)均≤2 分。术后两周内镇痛药总剂量为 1 剂(范围 0-25 剂)。6 例(5.3%)患者出现术后并发症:5 例为 Clavien-Dindo(C-D)分级 I 级,1 例为 C-D 分级 IIIa 级。1、3、5 年的累积成功率分别为 96.5%、85.3%和 85.3%。使用 10 分制评估患者满意度,术后每年均≥9 分。

结论

AM 手术是一种有效的非切除术,治疗 III 度痔具有满意的中期疗效,且并发症发生率低、术后镇痛需求低、患者满意度高。

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Int J Colorectal Dis. 2023 May 3;38(1):112. doi: 10.1007/s00384-023-04394-w.
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