Dehghan Ali, Soleimani Salehabadi Hossein, Jamshidi Ahmadreza, Kamali Zohre, Mali Mojgan, Faezi Seyedeh Tahereh, Baghdadi Azarakhsh, Alesaeidi Sogol, Sahraei Fatemeh, Azizi Niloufar, Zand Sanaz, Yasini Sara Sadat, Namazi Maryam, Daya Atefe, Nazemian Ryan, Shamsi Farimah, Nejadhosseinian Mohammad, Davatchi Fereydoun
Department of Internal Medicine, Shahid Sadoughi Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Rheumatology Research Center, Tehran University of Medical Sciences, North Amirabad Street, Tehran, 1411713137, Iran.
BMC Rheumatol. 2021 Nov 2;5(1):46. doi: 10.1186/s41927-021-00214-2.
The purpose of this study was to determine the prevalence of musculoskeletal complaints, rheumatologic diseases, and disability among the Zoroastrian population in Iran.
The city of Yazd, in central Iran was selected for this study, with the highest population of Zoroastrians in Iran. Subjects were selected by cluster sampling of 9 neighborhoods populated with Zoroastrians. Subjects ≥15 years old were interviewed by trained interviewers in their houses. The validated Farsi translation of Community Oriented Program for the Control of Rheumatic Disease (COPCORD) Core Questionnaire (CCQ) was used for this study. Subjects with musculoskeletal complaints (pain, stiffness and/or swelling) were examined by a rheumatologist. Laboratory tests and radiographic exams were performed when deemed necessary.
Two-thousand subjects were interviewed during a 12-month period, of which 956 were male, and 1044 were female. The mean age was 41.1 ± 18.3 years (95%CI: 40.3-41.9). 36.9% of the subjects had university-level education. In the 7 days prior to the interview, 27.6% of the subjects had musculoskeletal complaints, with the knee, dorsolumbar spine, and shoulder being the most common sites of complaints. The most common rheumatologic diagnoses were osteoarthritis (21.5%) and low back pain (10.3%). Rheumatoid arthritis was diagnosed in 1.2% of the subjects.
The epidemiology of musculoskeletal complaints and rheumatologic disorders was inconsistent with previous COPCORD studies in Iran, with a lower prevalence of musculoskeletal complaints in general, lower rates of Behçet and lupus, and a higher prevalence of rheumatoid arthritis. The findings of this study can be for development of better prevention, screening, and treatment programs for the vulnerable population of Zoroastrians in Iran.
本研究旨在确定伊朗琐罗亚斯德教人群中肌肉骨骼疾病、风湿性疾病及残疾的患病率。
本研究选取了伊朗中部的亚兹德市,该市是伊朗琐罗亚斯德教人口最多的城市。通过对9个有琐罗亚斯德教居民的社区进行整群抽样来选取研究对象。15岁及以上的研究对象由经过培训的访谈员在其家中进行访谈。本研究使用了经验证的面向社区的风湿性疾病控制项目(COPCORD)核心问卷(CCQ)的波斯语翻译版本。有肌肉骨骼疾病(疼痛、僵硬和/或肿胀)的研究对象由一名风湿病学家进行检查。必要时进行实验室检查和影像学检查。
在12个月的时间里,共访谈了2000名研究对象,其中男性956名,女性1044名。平均年龄为41.1±18.3岁(95%置信区间:40.3 - 41.9)。36.9%的研究对象拥有大学学历。在访谈前7天内,27.6%的研究对象有肌肉骨骼疾病,其中膝盖、胸腰椎和肩部是最常见的患病部位。最常见的风湿性疾病诊断为骨关节炎(21.5%)和腰痛(10.3%)。1.2%的研究对象被诊断为类风湿关节炎。
肌肉骨骼疾病和风湿性疾病的流行病学情况与伊朗之前的COPCORD研究不一致,总体上肌肉骨骼疾病的患病率较低,白塞病和狼疮的发病率较低,而类风湿关节炎的患病率较高。本研究结果可用于为伊朗脆弱的琐罗亚斯德教人群制定更好的预防、筛查和治疗方案。