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手术治疗Scheuermann 后凸畸形的研究进展:一项荟萃分析

Surgical Procedures Used for Correction of Scheuermann's Kyphosis: A Meta-Analysis.

机构信息

Fourth Department of Orthopedics, Handan Central Hospital of Hebei Province, Handan 056001, China.

出版信息

Pain Res Manag. 2021 Oct 23;2021:2142964. doi: 10.1155/2021/2142964. eCollection 2021.

Abstract

OBJECTIVES

Scheuermann's kyphosis can cause severe back pain and cosmetic disorders to patients. Previous studies on surgical procedure selection for correction of Scheuermann's kyphosis have drawn controversial conclusions. Here, a meta-analysis was performed to figure out a better way between anterior-posterior (AP) combined procedures and posterior-only (PO) procedures.

METHODS

We searched PubMed database and Ovid database, as well as Cochrane Library (between January 2009 and December 2020, around recent ten years), for studies reporting Scheuermann's kyphosis correction in an anterior way or a posterior way. Random effects meta-analysis regarding correction degrees and incidence of proximal junctional kyphosis (PJK) was performed.

RESULTS

Finally, 13 unique studies including 586 patients (AP: 300; PO: 286) were identified and included for this meta-analysis. Overall, 6 AP cohorts and 10 PO cohorts were pooled regarding the correction degrees of kyphosis in the analysis, respectively. Pooled correction degrees in AP cohorts were 33.31 (95% CI: 27.48-39.15;  = 86%, < 0.001) and in PO cohorts were 31.16 (95% CI: 26.97-35.35;  = 81.1%, < 0.001). Comparison of correction between AP and PO cohorts did not indicate any significant difference. Likewise, postoperative PJK incidence showed no difference. Back pain can be caused by both AP and PO procedures, but which causes less pain remains to be conclusive. The PO approach showed less blood loss and shorter surgical duration as compared to the AP approach.

CONCLUSIONS

In summary, this meta-analysis shows similar treatment effects between AP and PO procedures in correcting Scheuermann's kyphosis, suggesting the advantage of PO procedures due to less blood loss and surgical duration. However, the postoperative complications PJK and distal junctional kyphosis (DJK) cannot be well concluded due to the limitation of existing data.

摘要

目的

Scheuermann 后凸畸形可导致患者严重背痛和外观障碍。既往关于 Scheuermann 后凸畸形矫正手术方式选择的研究得出了相互矛盾的结论。本研究采用荟萃分析来比较前路-后路(AP)联合手术与单纯后路(PO)手术的优劣。

方法

我们检索了 PubMed 数据库、Ovid 数据库和 Cochrane 图书馆(2009 年 1 月至 2020 年 12 月,近 10 年),以获取采用前路或后路矫正 Scheuermann 后凸畸形的研究。采用随机效应荟萃分析比较两种术式的矫正程度和近端交界性后凸(PJK)的发生率。

结果

最终纳入了 13 项研究共 586 例患者(AP 组 300 例,PO 组 286 例)。分别对 6 项 AP 组和 10 项 PO 组的后凸矫正程度进行了荟萃分析。AP 组的平均矫正程度为 33.31°(95% CI:27.48°-39.15°;  = 86%, < 0.001),PO 组为 31.16°(95% CI:26.97°-35.35°;  = 81.1%, < 0.001)。AP 组与 PO 组之间的矫正程度无显著差异。同样,术后 PJK 发生率也无差异。后路和前路手术都可引起背痛,但哪种手术引起的疼痛更小仍存在争议。与前路手术相比,后路手术失血量较少,手术时间较短。

结论

综上所述,本荟萃分析表明,AP 和 PO 两种术式在治疗 Scheuermann 后凸畸形方面具有相似的疗效,后路手术因失血量少和手术时间短而具有一定优势。然而,由于现有数据的局限性,术后并发症 PJK 和远端交界性后凸(DJK)仍无法得出明确结论。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5bb1/8557059/8d5f0db91f7d/PRM2021-2142964.001.jpg

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