Zaki Muhammad, Muhammad Ariffin Mohd Hisam
Orthopaedics and Traumatology, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, MYS.
Spine Surgery, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, MYS.
Cureus. 2021 Sep 26;13(9):e18306. doi: 10.7759/cureus.18306. eCollection 2021 Sep.
For patients with pyogenic spondylodiscitis, medical therapy with antibiotics is the first line of treatment. Response to antibiotics can be assessed by improvement of symptoms, reduction in inflammatory markers, and radiological evidence of infection resolution with magnetic resonance imaging (MRI). We report a case of a 60-year-old man who presented with intermittent fever and persistent back pain. He was initially treated with an intravenous antibiotic for sepsis secondary to Salmonella enteritidis bacteremia. His spine MRI showed compression of the T10 vertebra with vertebral abnormality suggestive of metastases. He showed no clinical improvement after a course of intravenous antibiotics. Following that, debridement and spinal instrumentation of the thoracic vertebra were done in single-stage surgery.
对于化脓性脊椎椎间盘炎患者,抗生素药物治疗是一线治疗方法。可通过症状改善、炎症标志物降低以及磁共振成像(MRI)显示感染消退的影像学证据来评估对抗生素的反应。我们报告一例60岁男性病例,该患者表现为间歇性发热和持续性背痛。他最初因肠炎沙门氏菌菌血症继发败血症接受静脉抗生素治疗。他的脊柱MRI显示T10椎体受压,椎体异常提示转移。静脉使用抗生素一个疗程后,他的临床症状未改善。此后,在一期手术中对胸椎进行了清创和脊柱内固定术。