Pregnancy and Perinatology Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland.
Obstet Gynecol. 2022 Jan 1;139(1):3-8. doi: 10.1097/AOG.0000000000004636.
Three coronavirus disease 2019 (COVID-19) vaccines have been authorized for use in the United States; specifically, the Pfizer-BioNTech, Moderna, and Johnson & Johnson-Janssen COVID-19 vaccines were granted emergency use authorization by the U.S. Food and Drug Administration in late 2020 and early 2021. Vaccination coverage and intent among adults are lowest among those aged 18-39 years and among females in particular. In females of reproductive age, enthusiasm for receiving a COVID-19 vaccine may be negatively affected by claims currently circulating widely on diverse social media platforms regarding the vaccines adversely affecting fertility and pregnancy. Yet it is important to note that these claims are anecdotal in nature and not supported by the available scientific evidence. It is also imperative that the effects of COVID-19 vaccine on reproductive health are clarified. Herein, we discuss the existing scientific data supporting COVID-19 vaccine safety and efficacy in people who are planning to conceive or who are pregnant or lactating and highlight the importance of COVID-19 vaccination in females of reproductive age.
三种新型冠状病毒疾病 2019 (COVID-19) 疫苗已在美国获准使用；具体而言，辉瑞-生物技术公司、莫德纳公司和强生公司 - 杨森 COVID-19 疫苗于 2020 年末和 2021 年初获得美国食品和药物管理局的紧急使用授权。在成年人中，18-39 岁年龄组和女性的疫苗接种率和接种意愿最低。在育龄女性中，对 COVID-19 疫苗的接受意愿可能会受到目前在各种社交媒体平台上广泛流传的关于疫苗对生育和怀孕有不利影响的说法的负面影响。然而，重要的是要注意，这些说法是轶事性质的，没有得到现有科学证据的支持。同样至关重要的是，需要阐明 COVID-19 疫苗对生殖健康的影响。在此，我们讨论了现有的科学数据，这些数据支持计划怀孕、怀孕或哺乳的人群接种 COVID-19 疫苗的安全性和有效性，并强调了 COVID-19 疫苗在育龄女性中的重要性。
