Department of Epidemiology and Biostatistics, University of Georgia, Athens, GA.
Department of Pediatrics, Massachusetts General Hospital and Harvard Medical School, Boston, MA.
Mayo Clin Proc. 2021 Dec;96(12):2991-3000. doi: 10.1016/j.mayocp.2021.07.021. Epub 2021 Oct 30.
To examine pharmacotherapy for obesity in the United States from 2011 to 2016 using a large, nationally representative sample.
Data were obtained during 6 years, 2011 to 2016, from the National Ambulatory Medical Care Survey. There were 3 types of visits identified: patients with obesity and an antiobesity drug mention; patients with obesity and no antiobesity drug mention; and patients without obesity and with antiobesity drug mention. The χ test was used to compare characteristics across each type of visit. To predict the odds of an antiobesity medication mention for patients with obesity, a logistic regression analysis was conducted.
Of the overall weighted 196,872,870 office-based physician visits made by patients with obesity from 2011 to 2016, 1% mentioned an antiobesity drug. In addition, there were 760,470 office-based physician visits by patients without obesity but with an antiobesity medication mention. An antiobesity drug mention was more likely for those aged 51 years or older and those residing in the South (adjusted odds ratio, 5.31 95% CI, 1.19 to 23.59).
There was a slight increase in antiobesity medication mentions, from 0.26% in 2011 to 0.28% in 2016, but only 1% of office-based visits for patients with obesity received a prescription for an antiobesity medication. Physicians tended to prescribe antiobesity medications to those with obesity aged 51 years or older and residing in the South. Antiobesity medication for treatment of obesity is significantly underused.
使用大型全国代表性样本研究 2011 年至 2016 年美国肥胖症的药物治疗情况。
数据来源于 2011 年至 2016 年的全国门诊医疗调查,共 6 年。确定了 3 种就诊类型:肥胖且提及抗肥胖药物的患者;肥胖但未提及抗肥胖药物的患者;非肥胖且提及抗肥胖药物的患者。采用 χ 检验比较各类型就诊患者的特征。为预测肥胖患者提及抗肥胖药物的可能性,进行了 logistic 回归分析。
在 2011 年至 2016 年间,肥胖患者共进行了 196872870 次门诊就诊,其中 1%的就诊提及抗肥胖药物。此外,还有 760470 次非肥胖患者但提及抗肥胖药物的门诊就诊。年龄在 51 岁或以上和居住在南部的患者更有可能提及抗肥胖药物(调整后的优势比,5.31;95%CI,1.19 至 23.59)。
抗肥胖药物的提及率略有上升,从 2011 年的 0.26%上升至 2016 年的 0.28%,但只有 1%的肥胖患者门诊就诊获得了抗肥胖药物处方。医生倾向于为年龄在 51 岁或以上和居住在南部的肥胖患者开抗肥胖药物。用于治疗肥胖症的抗肥胖药物明显未得到充分使用。