Department of Occupational Therapy, School of Health Professions, University of Alabama at Birmingham, Birmingham, Alabama.
School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Arch Phys Med Rehabil. 2022 Feb;103(2):331-335. doi: 10.1016/j.apmr.2021.10.011. Epub 2021 Oct 30.
To determine differences in obesity, type 2 diabetes, and hypertension in Black patients compared with White patients with multiple sclerosis (MS).
Cross-sectional database review.
Large academic medical center research records database.
A total of 3191 patient cases (N=3191; 77% female, 34% Black) identified by MS diagnosis within the medical record.
Not applicable.
Diagnosis codes for type 2 diabetes and hypertension. Body mass index (BMI), race, age, and sex were collected. Analysis of variance (continuous variables) and chi-square analyses (categorical variables) were conducted to determine differences in obesity, diabetes, and hypertension between race and sex. Logistic regression was conducted to determine odds ratios (ORs) of developing diabetes and hypertension based on race, sex, BMI, and age.
Black patients were more than twice as likely to be diagnosed as having diabetes (OR, 2.15 [95% CI, 1.70-2.72]; P<.0001) or hypertension (OR, 2.44 [95% CI, 2.05-2.91], P<.0001) compared with White patients. Sex did not present a greater likelihood of being diagnosed as having diabetes; however, men were 1.22 times more likely be diagnosed as having hypertension compared with women (95% CI, 1.01-1.49; P=.0439). Increased age and BMI were also significantly associated with likelihood of diagnosis of diabetes and hypertension (age: diabetes OR, 1.05 [95% CI, 1.04-1.06], P<.0001; hypertension OR, 1.06 [95% CI, 1.05-1.06], P<.0001; BMI: diabetes obese vs normal: OR, 2.11 [95% CI, 1.43-3.11], P=.0002; hypertension: obese vs normal: OR, 1.72 [95% CI, 1.39-2.13], P<.0001).
Black patients with MS are significantly more likely to have cardiometabolic conditions than White patients. These conditions have been associated with poorer health outcomes for people with MS and may have some effect on the differences in MS disease course reported in Black patients.
比较多发性硬化症（MS）黑人患者与白人患者的肥胖、2 型糖尿病和高血压差异。
横断面数据库回顾。
大型学术医疗中心研究记录数据库。
通过病历中 MS 诊断共确定 3191 例患者病例（N=3191；77%女性，34%黑人）。
不适用。
2 型糖尿病和高血压诊断代码。收集体重指数（BMI）、种族、年龄和性别。采用方差分析（连续变量）和卡方分析（分类变量）比较不同种族和性别的肥胖、糖尿病和高血压差异。采用 logistic 回归分析根据种族、性别、BMI 和年龄确定患糖尿病和高血压的优势比（OR）。
黑人患者被诊断患有糖尿病（OR，2.15 [95%CI，1.70-2.72]；P<.0001）或高血压（OR，2.44 [95%CI，2.05-2.91]，P<.0001）的可能性是白人患者的两倍多。性别并不能增加被诊断患有糖尿病的可能性；然而，与女性相比，男性患高血压的可能性高 1.22 倍（95%CI，1.01-1.49；P=.0439）。年龄和 BMI 增加也与糖尿病和高血压的诊断可能性显著相关（年龄：糖尿病 OR，1.05 [95%CI，1.04-1.06]，P<.0001；高血压 OR，1.06 [95%CI，1.05-1.06]，P<.0001；BMI：糖尿病肥胖与正常：OR，2.11 [95%CI，1.43-3.11]，P=.0002；高血压：肥胖与正常：OR，1.72 [95%CI，1.39-2.13]，P<.0001）。
多发性硬化症的黑人患者比白人患者更有可能出现心血管代谢疾病。这些情况与多发性硬化症患者的健康状况较差有关，并且可能对黑人群体报告的多发性硬化症病程差异有一定影响。
