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女性接受性腺毒性治疗时的生育力保存选择。

Options for preserving fertility in women undergoing gonadotoxic treatment.

机构信息

Chair, Department of Subspecialty Care for Women's Health, Cleveland Clinic, Cleveland, OH

出版信息

Cleve Clin J Med. 2021 Nov 2;88(11):607-612. doi: 10.3949/ccjm.88gr.21001.

Abstract

Cancer chemotherapy and radiotherapy can be toxic to the ovaries, but women can improve their chances of preserving their fertility. Three options are available: gonadotropin-releasing hormone (GnRH) analogues, oocyte cryopreservation, and ovarian tissue cryopreservation. A fourth option, ovarian transposition, is valid for patients undergoing pelvic radiation but is not useful in patients undergoing chemotherapy.

摘要

癌症的化疗和放疗可能对卵巢有毒性,但女性可以提高其保留生育能力的机会。有三种选择:促性腺激素释放激素(GnRH)类似物、卵母细胞冷冻保存和卵巢组织冷冻保存。第四种选择是卵巢移位,适用于接受盆腔放疗的患者,但对接受化疗的患者没有用。

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