[Antibody-dependent cytotoxicity of lymphocytes in acute myeloblastic leukemia and chronic myelocytic leukemia].

Antibody-dependent cytotoxicity (ADC) of peripheral blood blast cells in vitro was studied in 16 patients with acute myeloid leukemia (AML), 6 patients with acute monoblastic leukemia (AMonL), and 13 patients with acute myelomonoblastic leukemia (AMmL). It was found that monoblasts have a higher degree of ADC activities with respect to target cells than myeloblasts. Functional differences between monoblasts and myeloblasts may be used as criteria for differential diagnosis of acute leukemia variants.