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光疗设备的辐照度足迹:一项比较研究。

Irradiance footprint of phototherapy devices: a comparative study.

机构信息

Medical Physics Department, Isala Hospital, Zwolle, The Netherlands.

Biomedical Photonic Imaging group, Technical Medical Centre, University of Twente, Enschede, The Netherlands.

出版信息

Pediatr Res. 2022 Aug;92(2):453-458. doi: 10.1038/s41390-021-01795-x. Epub 2021 Nov 2.

Abstract

BACKGROUND

Phototherapy (PT) is the standard treatment of neonatal unconjugated hyperbilirubinemia. The irradiance footprint, i.e., the illuminated area by the PT device with sufficient spectral irradiance, is essential for PT to be effective. Irradiance footprint measurements are not performed in current clinical practice. We describe a user-friendly method to systematically evaluate the high spectral irradiance (HSI) footprint (illuminated area with spectral irradiance of ≥30 μW cm nm) of PT devices in clinical practice.

MATERIALS AND METHODS

Six commercially available LED-based overhead PT devices were evaluated in overhead configuration with an incubator. Spectral irradiance (µW cm nm) and HSI footprint were measured with a radiospectrometer (BiliBlanket Meter II).

RESULTS

The average measured spectral irradiance ranged between 27 and 52 μW cm nm and HSI footprint ranged between 67 and 1465 cm, respectively. Three, two, and one PT devices out of six covered the average BSA of an infant born at 22, 26-32, and 40 weeks of gestation, respectively.

CONCLUSION

Spectral irradiance of LED-based overhead PT devices is often lower than manufacturer's specifications, and HSI footprints not always cover the average BSA of a newborn infant. The proposed measurement method will contribute to awareness of the importance of irradiance level as well as footprint measurements in the management of neonatal jaundice.

IMPACT

While a sufficient spectral irradiance footprint is essential for PT to be effective, some PT devices have spectral irradiance footprints that are too small to cover the entire body surface area (BSA) of a newborn infant. This study introduces a user-friendly, accessible method to systematically evaluate the spectral irradiance level and footprint of PT devices. This study supports awareness on the role of the spectral irradiance footprint in the efficacy of PT devices. Irradiance footprint can be easily measured during phototherapy with the proposed method.

摘要

背景

光疗(PT)是治疗新生儿未结合高胆红素血症的标准治疗方法。辐照度足迹,即具有足够光谱辐照度的 PT 设备的照明区域,对于 PT 有效至关重要。目前的临床实践中没有进行辐照度足迹测量。我们描述了一种用户友好的方法,用于系统地评估 PT 设备的高光谱辐照度(HSI)足迹(具有≥30μW·cm·nm 光谱辐照度的照明区域)。

材料与方法

在装有孵化器的顶棚配置下,评估了六台市售的基于 LED 的顶棚 PT 设备。使用辐射光谱仪(BiliBlanket Meter II)测量光谱辐照度(µW·cm·nm)和 HSI 足迹。

结果

平均测量的光谱辐照度范围在 27 到 52μW·cm·nm 之间,HSI 足迹范围在 67 到 1465cm 之间。六台 PT 设备中的三台、两台和一台分别覆盖了 22 周、26-32 周和 40 周胎龄出生婴儿的平均 BSA。

结论

基于 LED 的顶棚 PT 设备的光谱辐照度通常低于制造商的规格,并且 HSI 足迹并不总是覆盖新生儿的平均 BSA。所提出的测量方法将有助于提高对辐照度水平以及在新生儿黄疸管理中足迹测量的重要性的认识。

影响

虽然足够的光谱辐照度足迹对于 PT 的有效性至关重要,但一些 PT 设备的光谱辐照度足迹太小,无法覆盖新生儿的整个体表面积(BSA)。本研究介绍了一种用户友好、易于使用的方法,用于系统地评估 PT 设备的光谱辐照度水平和足迹。该研究支持在 PT 设备的疗效中对光谱辐照度足迹作用的认识。可以使用建议的方法在光疗期间轻松测量辐照度足迹。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4c3/9522581/324c47d83293/41390_2021_1795_Fig1_HTML.jpg

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