Ophthalmology (Muramatsu, Fukushima, Kudo), Oncology (Ono), and Cardiology (Hirao), Japan Animal Referral Medical Center, 2-5-8 Kuji, Takatsu-ku, Kawasaki-shi, Kanagawa 213-0032, Japan and Akatsuka Dog & Cat Hospital (Akatsuka), 5-6-21 Kitaterao, Tsurumi-ku, Yokohama-shi, Kanagawa 234-0074, Japan.
Can Vet J. 2021 Nov;62(11):1185-1189.
A 13-year-old, male Pomeranian dog was presented for scleral rupture with intraocular hemorrhage and retinal detachment in the right eye. After intrascleral silicone ball prosthesis, recurrent swelling and granulomatous blepharitis were observed for 140 d and finally melting keratitis developed. Although an intraorbital prosthesis was implanted, recurrent, serious, erosive, and ulcerative blepharitis developed with high plasma C-reactive protein concentrations. Since the blepharitis could not be controlled, the silicone ball was removed and the affected orbit was debrided. The blepharitis resolved rapidly, and the orbit healed routinely. Positive allergic reactions to silicone were discovered through a patch test. Key clinical message: To the authors' knowledge, this is the first report on silicone allergy in a dog with positive allergic reactions to silicone in the patch test.
一只 13 岁雄性博美犬因右眼巩膜破裂伴眼内出血和视网膜脱离就诊。在右眼行巩膜内硅橡胶球假体植入术后 140 天，出现复发性肿胀和肉芽肿性睑炎，最终发展为角膜融解。尽管植入了眼眶内假体，但仍出现复发性、严重、侵蚀性和溃疡性睑炎，且血浆 C 反应蛋白浓度较高。由于睑炎无法控制，因此取出了硅橡胶球，并对受累的眼眶进行清创。睑炎迅速缓解，眼眶常规愈合。通过斑贴试验发现对硅橡胶存在阳性过敏反应。
据作者所知，这是首例报道的对硅橡胶过敏的犬，其斑贴试验呈阳性过敏反应。
