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评估非侵入性检查作为诊断工具在评估前尿道狭窄男性膀胱出口梗阻严重程度中的作用。

Evaluation of non-invasive tests as diagnostic tools in assessment of bladder outlet obstruction severity in men with anterior urethral stricture.

作者信息

Krukowski Jakub, Kałużny Adam, Kłącz Jakub, Piątkowska Anna, Matuszewski Marcin

机构信息

Department of Urology, Medical University of Gdańsk, Gdańsk, Poland.

出版信息

Cent European J Urol. 2021;74(3):422-428. doi: 10.5173/ceju.2021.3.153.R1. Epub 2021 Jul 27.

DOI:10.5173/ceju.2021.3.153.R1
PMID:34729232
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8552944/
Abstract

INTRODUCTION

The aim of this article was to evaluate non-invasive tests, which were typically used in preoperative diagnosis of male patients with anterior urethral strictures in the assessment of the urethral resistance caused by urethral occlusion.

MATERIAL AND METHODS

A total of 63 adult males with confirmed urethral stricture and aged below 55 years old were enrolled in the study. Data obtained from non-invasive tests such as uroflowmetry (UF), ultrasound examination (USG), and questionnaires such as from The International Prostatic Symptom Score (IPSS), and The Patient-Reported Outcome Measure for Urethral Stricture Surgery (USS-PROM) were analyzed.

RESULTS

Among all analyzed non-invasive tests, bladder wall thickness (BWT) showed the highest correlation with the degree of urethral occlusion described as percentage of preserved urethral lumen (r = -0.70; p <0.0001). UF variables presented medium degree of correlation, with maximum flow rate (Qmax) as the best parameter (p = 0.45; p = 0.0005). Results from both questionnaires did not show any correlation with the severity of the urethral stricture. Multiple linear regression analysis showed that only BWT was an independent predictor in detection degree of urethral occlusion.

CONCLUSIONS

UF and USG seem to be useful additional diagnostic tools in assessment severity of urethral occlusion in men suffering from anterior urethral stricture. Among them, USG had the highest correlation with degree of urethral occlusion.

摘要

引言

本文旨在评估非侵入性检查,这些检查通常用于男性前尿道狭窄患者的术前诊断,以评估尿道闭塞引起的尿道阻力。

材料与方法

共有63名确诊为尿道狭窄且年龄在55岁以下的成年男性纳入本研究。分析了从诸如尿流率测定(UF)、超声检查(USG)等非侵入性检查以及诸如国际前列腺症状评分(IPSS)和尿道狭窄手术患者报告结局测量(USS-PROM)等问卷中获得的数据。

结果

在所有分析的非侵入性检查中,膀胱壁厚度(BWT)与以保留尿道腔百分比表示的尿道闭塞程度相关性最高(r = -0.70;p <0.0001)。UF变量呈现中等程度的相关性,其中最大尿流率(Qmax)是最佳参数(p = 0.45;p = 0.0005)。两份问卷的结果均未显示与尿道狭窄的严重程度有任何相关性。多元线性回归分析表明,只有BWT是尿道闭塞检测程度的独立预测因子。

结论

UF和USG似乎是评估男性前尿道狭窄患者尿道闭塞严重程度的有用辅助诊断工具。其中,USG与尿道闭塞程度的相关性最高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb39/8552944/80eb522678e0/CEJU-74-153.R1-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb39/8552944/638655a5b3d2/CEJU-74-153.R1-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb39/8552944/80eb522678e0/CEJU-74-153.R1-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb39/8552944/638655a5b3d2/CEJU-74-153.R1-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb39/8552944/80eb522678e0/CEJU-74-153.R1-g002.jpg

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Evaluation of outcomes of Urethral Stricture Surgery: psychometric validation of a Polish language version of the Patient-Reported Outcome Measure for urethral stricture surgery.
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A Comprehensive Review Emphasizing Anatomy, Etiology, Diagnosis, and Treatment of Male Urethral Stricture Disease.男性尿道狭窄疾病的解剖学、病因学、诊断和治疗的综合综述
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Computational Fluid Dynamic Modeling of Urethral Strictures.尿道狭窄的计算流体动力学建模。
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