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妊娠子宫完全破裂:一项10年回顾性描述性研究

Complete Rupture of the Pregnant Uterus: A 10-year Retrospective Descriptive Study.

作者信息

Zhou Qiong, Zhou Xuan, Feng Ling, Wang Shao-Shuai

机构信息

Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.

出版信息

Curr Med Sci. 2022 Feb;42(1):177-184. doi: 10.1007/s11596-021-2460-9. Epub 2021 Nov 3.

Abstract

OBJECTIVE

The goal of this work is to analyze the incidence, etiology, clinical characteristics, maternal and neonatal outcomes of complete uterine rupture during pregnancy.

METHODS

The information of complete uterine rupture between June 2010 and May 2020 was investigated retrospectively at a tertiary center, and included demographic data, delivery characteristics, intraoperative findings, and maternal and neonatal outcomes. The prevalence rate of uterine rupture in the early group (hospitalized from June 2010 to May 2015) and late group (June 2015 to May 2020) was compared and analyzed.

RESULTS

There were 37 (0.056%) cases of complete uterine rupture in 66 092 births, including 27 (0.041%) of scar uterus and 10 (0.015%) of non-scarred uterus. High-risk factors for scarred uterine rupture included: previous cesarean section (13, 48.1%), myomectomy (8, 29.6%), corneal pregnancy resection (6, 22.2%), history of uterine rupture (1, 3.7%), and uterus perforation during abortion (1, 3.7%). Compared to the early group, the number of uterine ruptures caused by previous cesarean section was significantly reduced in the late group. Of the 10 patients with non-scarred uterine rupture, 3 (30%) occurred during delivery and 7 (70%) were spontaneous. Among the 37 complete rupture patients, 3 (8.1%) died of uterine scar rupture, 19 (51.3%) cases were reported with fetal/newborn deaths, 5 (13.5%) cases underwent hysterectomy and the rest were treated with uterine repair.

CONCLUSION

Complete uterine rupture often has catastrophic effect on pregnancy outcomes. Obstetrics doctors should be vigilant to identify the risk factors and clinical presentations of uterine rupture during pregnancy. Strict prenatal management is beneficial to improve pregnancy outcomes.

摘要

目的

本研究旨在分析妊娠期完全性子宫破裂的发生率、病因、临床特征、孕产妇及新生儿结局。

方法

回顾性调查某三级中心2010年6月至2020年5月期间完全性子宫破裂的相关信息,包括人口统计学数据、分娩特征、术中所见以及孕产妇和新生儿结局。比较并分析早期组(2010年6月至2015年5月住院)和晚期组(2015年6月至2020年5月)子宫破裂的发生率。

结果

66092例分娩中有37例(0.056%)发生完全性子宫破裂,其中瘢痕子宫27例(0.041%),非瘢痕子宫10例(0.015%)。瘢痕子宫破裂的高危因素包括:既往剖宫产史(13例,48.1%)、子宫肌瘤切除术(8例,29.6%)、子宫角部妊娠切除术(6例,22.2%)、子宫破裂史(1例,3.7%)以及人工流产时子宫穿孔(1例,3.7%)。与早期组相比,晚期组既往剖宫产所致子宫破裂的数量显著减少。10例非瘢痕子宫破裂患者中,3例(30%)发生在分娩期间,7例(70%)为自发性破裂。37例完全性破裂患者中,3例(8.1%)死于子宫瘢痕破裂,19例(51.3%)出现胎儿/新生儿死亡,5例(13.5%)行子宫切除术,其余患者接受子宫修补术治疗。

结论

完全性子宫破裂常对妊娠结局产生灾难性影响。产科医生应警惕识别妊娠期子宫破裂的危险因素和临床表现。严格的产前管理有助于改善妊娠结局。

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