Division of Cardiovascular and Thoracic Surgery, Department of Surgery, 22957Duke University School of Medicine, USA.
Asian Cardiovasc Thorac Ann. 2022 Mar;30(3):364-370. doi: 10.1177/02184923211054693. Epub 2021 Nov 3.
This review discusses the management of acute Type A aortic dissection (ATAAD) complicated by cerebral malperfusion (CMP). While prompt surgical repair is the accepted standard of care for ATAAD, there remains uncertainty and debate about the optimal management of the subgroup of ATAAD patients with CMP. Examined topics include overall survival and neurologic outcomes after surgical repair of ATAAD with CMP, how the severity of presenting neurologic deficits impacts the decision and timing of operation, predictors of postoperative neurologic recovery, and a suggested management algorithm for ATAAD with CMP based upon the best available clinical evidence.
这篇综述讨论了急性 A 型主动脉夹层(ATAAD)合并脑灌注不良(CMP)的治疗管理。虽然及时的手术修复是 ATAAD 的公认治疗标准,但对于 CMP 的 ATAAD 亚组患者的最佳治疗管理仍存在不确定性和争议。检查的主题包括 CMP 合并 ATAAD 手术后的总体存活率和神经结局、现有神经缺陷的严重程度如何影响手术的决策和时机、术后神经恢复的预测因素,以及基于现有最佳临床证据为 CMP 合并 ATAAD 提出的管理算法。