Department of Trauma, Hand, and Reconstructive Surgery, University Hospital Münster; Institute of Biometrics and Clinical Research, University Hospital Münster; Department of Radiology, University Hospital Münster; Medical Management, Medical Controlling, University Hospital Münster.
Dtsch Arztebl Int. 2021 Dec 3;118(48):817-823. doi: 10.3238/arztebl.m2021.0326.
The goal of this study is to compare mortality, major adverse events, and complication rates after the surgical treatment of proximal humeral fractures with locked plate fixation (LPF) versus reverse total shoulder arthroplasty (RTSA) in elderly patients.
Health insurance data from patients aged 65 and above for the period January 2010 to September 2018 were retrospectively evaluated. The median follow-up duration after LPF (40 419 patients) or RTSA (13 552 patients) was 52 months. Hazard ratios adapted to the patients' risk profiles were determined with the aid of multivariable Cox regression models. The p-values were adjusted using the Bonferroni-Holm method.
After adaptation to the patients' risk profiles, reverse shoulder replacement showed statistically significantly lower mortality (HR 0.92, 95% confidence interval [0.88; 0.95]; p <0.001) and fewer major adverse events (HR 0.92 [0.89; 0.95]; p<0.001). Eight years after surgery, the risk of surgical complications was twice as high for LPF (12.2% [11.9; 12.7]; HR for RTSA versus LPF 0.5 [0.46; 0.55]; p<0.001 for both), with 3.8% [3.6; 4.0] of the patients receiving a secondary RTSA. Surgical complications were more common (p<0.05) in patients with a diagnosis of osteo - porosis, obesity, alcohol abuse, chronic polyarthritis, or frozen shoulder.
The long-term findings are in agreement with clinical short-term findings from other studies and support the current trend toward more liberal use of reverse shoulder replacements in elderly patients.
本研究旨在比较老年患者肱骨近端骨折采用锁定钢板固定(LPF)与反式全肩关节置换术(RTSA)治疗后的死亡率、主要不良事件和并发症发生率。
回顾性分析了 2010 年 1 月至 2018 年 9 月期间年龄在 65 岁及以上的患者的健康保险数据。LPF(40419 例)或 RTSA(13552 例)后的中位随访时间为 52 个月。采用多变量 Cox 回归模型,根据患者的风险状况调整风险比。使用 Bonferroni-Holm 方法调整 p 值。
根据患者的风险状况进行调整后,反式肩关节置换术的死亡率显著降低(HR 0.92,95%置信区间 [0.88;0.95];p<0.001),主要不良事件更少(HR 0.92 [0.89;0.95];p<0.001)。术后 8 年,LPF 的手术并发症风险高 2 倍(12.2% [11.9;12.7];HR 为 RTSA 与 LPF 的 0.5 [0.46;0.55];p<0.001),有 3.8% [3.6;4.0]的患者接受了二次 RTSA。骨质疏松症、肥胖症、酗酒、慢性多关节炎或冻结肩等诊断的患者手术并发症更常见(p<0.05)。
长期结果与其他研究的临床短期结果一致,支持目前在老年患者中更广泛使用反式肩关节置换术的趋势。