College of Chemistry, Chemical Engineering and Materials Science, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Institute of Molecular and Nano Science, Shandong Normal University, Jinan 250014, P. R. China.
Chem Commun (Camb). 2021 Nov 19;57(92):12301-12304. doi: 10.1039/d1cc05442b.
Herein, we developed a triple-line lateral flow strip-based platform combined with an miRNA-initiated cyclic chain displacement reaction for the rapid and simultaneous dual-miRNA detection of lung cancer in a single strip test. The simultaneous dual-miRNA detection platform was used for the analysis of clinical serum samples, and distinguished non-small cell lung cancer patients from heathy individuals.
在这里，我们开发了一种三线侧向流条带平台，结合 miRNA 引发的循环链位移反应，用于在单个条带测试中快速同时双重 miRNA 检测肺癌。同时双重 miRNA 检测平台用于分析临床血清样本，并将非小细胞肺癌患者与健康个体区分开来。
