Postgraduate Program in Health Sciences, Universidade Federal de Viçosa - Viçosa (MG), Brazil.
Department of Medicine and Nursing, Universidade Federal de Viçosa - Viçosa (MG), Brazil.
Rev Bras Epidemiol. 2021 Oct 29;24:e210052. doi: 10.1590/1980-549720210052. eCollection 2021.
To analyze the characteristics and the factors associated with mortality of cases hospitalized for severe acute respiratory syndrome in a health region, in pre-pandemic and pandemic periods.
A retrospective documentary study of epidemiological surveillance carried out with secondary data from the Influenza Epidemiological Surveillance Information System, regarding the cases of patients belonging to a health region of Minas Gerais, Brazil.
During the pandemic period, there was an increase in the number of hospitalizations and deaths due to severe acute respiratory syndrome, in addition to differences between sociodemographic and clinical-epidemiological characteristics. In both periods, the age and the use of invasive ventilatory support were the predictors of hospital mortality. The mortality in the pandemic period was also associated with male gender, presence of risk factors, admission to an intensive care unit, use of non-invasive ventilatory support, and infection by COVID-19.
In 2020, the detection rate of severe acute respiratory syndrome was 21 times higher than in 2019 and new symptoms, such as anosmia and ageusia, were included in their investigation. In both periods evaluated, elderly patients and patients on invasive mechanical ventilation had a higher risk of mortality. With the pandemic, there was a greater number of hospitalizations and factors associated with mortality.
分析某卫生区域在大流行前和大流行期间因严重急性呼吸综合征住院病例的特征和死亡相关因素。
采用巴西米纳斯吉拉斯州某卫生区域流感监测信息系统的二级数据进行回顾性文献研究，对患者病例进行流行病学监测。
大流行期间，严重急性呼吸综合征的住院和死亡人数增加，且社会人口学和临床流行病学特征存在差异。在两个时期，年龄和有创性通气支持的使用都是住院死亡率的预测因素。大流行期间的死亡率还与男性、存在危险因素、入住重症监护病房、使用无创通气支持以及感染 COVID-19 有关。
2020 年，严重急性呼吸综合征的检出率是 2019 年的 21 倍，且对其进行调查时纳入了新的症状，如嗅觉丧失和味觉丧失。在两个评估时期，老年患者和接受有创机械通气的患者的死亡率更高。随着大流行的发展，住院人数和与死亡率相关的因素都有所增加。
