Choroidal metastases arising from carcinoma of the breast. Review and analysis of five cases.

Five cases of breast carcinoma metastasizing to the choroid were investigated and compared with the current literature. Choroidal metastases were found to bear an unfavorable prognostic factor (median survival of 11 months), and are related to heavy metastatic involvement even when the latter is not evident. Two patients responded to treatment, one to irradiation and one to systemic chemotherapy. The peak incidence is in perimenopasual women (mean age 48.2) which suggests that in this group of patients ocular examination may be advised for the routine followup.