Bowman B U
J Med. 1986;17(3-4):167-77.
Tonsillar lymphocytes from individuals between the ages of 4 and 32 were found to have K cell activity by a plaque assay on chicken erythrocytes. The activity was lower than that of peripheral blood lymphocytes from normal individuals. The K cell activity of tonsillar lymphocytes could only be demonstrated when the cells were isolated in the presence of indomethacin. Prostaglandin E2 (PGE2) was shown to be liberated in tonsillar breis prepared in the absence of indomethacin but not in its presence. It is suggested that PGE2 in vitro inhibits K cell activity of tonsillar lymphocytes.
通过对鸡红细胞进行空斑试验发现，4至32岁个体的扁桃体淋巴细胞具有K细胞活性。该活性低于正常个体外周血淋巴细胞的活性。只有当细胞在吲哚美辛存在的情况下分离时，扁桃体淋巴细胞的K细胞活性才能被证实。前列腺素E2（PGE2）在无吲哚美辛制备的扁桃体匀浆中会释放出来，但在有吲哚美辛存在时则不会。提示体外PGE2可抑制扁桃体淋巴细胞的K细胞活性。
