From the Department of Radiology (Aksu); and from the Department of Internal Medicine (Uslu, Tarhan, Karagülle), Yunus Emre State Hospital, Eskişehir, Turkey.
Saudi Med J. 2021 Nov;42(11):1223-1228. doi: 10.15537/smj.2021.42.11.20210485.
To investigate the relationship of the neutrophil lymphocyte ratio (NLR) and the platelet lymphocyte ratio (PLR) with lung involvement and total lung severity score (TLSS) in computed tomography (CT) of patients with coronavirus disease -19 (COVID-19) and to evaluate their clinical usability.
Basic laboratory, clinical features and imaging data of patients was obtained by examining the file and archive records of our hospital. According to the findings of lung CT scan at the time of diagnosis among COVID-19 patients, 2 groups were formed.
The NLR was 2.22±11.15 and the PLR was 142.77±387.10 in patients with COVID-19 pneumonia. The NLR was 1.88±7.47 and the PLR was 130.65±203.6 8 in patients without COVID-19 pneumonia. The differences in the NLR and the PLR were determined to be statistically significant between the 2 groups. A positive correlation was observed between NLR and PLR (r=0.225, =0.010) and TLSS (r=0.244, =0.005).
This study showed that the NLR and PLR values can be 2 inflammatory markers that can be used to evaluate lung involvement and disease severity in COVID-19 patients. At the time of initial diagnosis and during follow-up, these markers can give an idea in terms of prognosis, together with other clinical findings and markers.
研究中性粒细胞与淋巴细胞比值（NLR）和血小板与淋巴细胞比值（PLR）与新型冠状病毒病-19（COVID-19）患者计算机断层扫描（CT）中的肺受累和总肺严重程度评分（TLSS）的关系，并评估其临床应用价值。
通过查阅我院病历档案，获得患者的基本实验室、临床特征和影像学资料。根据 COVID-19 患者诊断时的肺部 CT 扫描结果，将患者分为两组。
COVID-19 肺炎患者的 NLR 为 2.22±11.15，PLR 为 142.77±387.10；非 COVID-19 肺炎患者的 NLR 为 1.88±7.47，PLR 为 130.65±203.68。两组间 NLR 和 PLR 差异有统计学意义。NLR 和 PLR 与 TLSS 呈正相关（r=0.225，P=0.010；r=0.244，P=0.005）。
本研究表明，NLR 和 PLR 值可以作为评估 COVID-19 患者肺受累和疾病严重程度的 2 种炎症标志物。在初始诊断和随访时，这些标志物可与其他临床发现和标志物一起提供预后信息。
