Serrano Javier, Crespo Patricia Calvo, Taboada Begoña, Gonzalez Ana Alvarez, García Rafael Garcia, Caamaño Antonio Gomez, Reyes Juan Carlos Trujillo, Mielgo-Rubio Xabier, Couñago Felipe
Department of Radiation Therapy, Clinica Universidad de Navarra, Madrid 28027, Spain.
Department of Radiation Oncology, Hospital Clínico Universitario Santiago de Compostela, Santiago de Compostela 15706, Spain.
World J Clin Oncol. 2021 Oct 24;12(10):833-844. doi: 10.5306/wjco.v12.i10.833.
This manuscript collects in a joint and orderly manner the existing evidence at the present time about postoperative treatment with radiotherapy in non-small cell lung cancer. It also systematically reviews the current evidence, the international recommendations in the most relevant guidelines, the most controversial aspects in clinical and pathological staging, the specific technical aspects of radiotherapy treatment, and also collects all the potential risk factors that have been postulated as significant in the prognosis of these patients, evaluating the possibility of segmenting a particularly sensitive subpopulation with a high risk of relapse on which an adjuvant treatment with radiotherapy could have an impact on their clinical evolution. Finally, currently active trials that aspire to provide more evidence on this topic are reviewed.
本手稿以联合且有序的方式收集了目前关于非小细胞肺癌术后放疗治疗的现有证据。它还系统地回顾了当前证据、最相关指南中的国际建议、临床和病理分期中最具争议的方面、放射治疗的具体技术方面，并且收集了所有被假定对这些患者预后有重大影响的潜在风险因素，评估了划分出一个具有高复发风险的特别敏感亚群的可能性，针对该亚群进行放疗辅助治疗可能会对其临床病程产生影响。最后，对目前正在进行的旨在提供更多关于该主题证据的试验进行了综述。
