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双波长铜蒸气激光成功治疗眼睑皮内黑素细胞痣(米舍尔痣)

The Successful Treatment of Eyelid Intradermal Melanocytic Nevi (Nevus of Miescher)With the Dual-Wavelengths Copper Vapor Laser.

作者信息

Ponomarev Igor Vladimirovich, Topchiy Sergey B, Andrusenko Yury N, Shakina Lyudmila D

机构信息

P.N. Lebedev Physical Institute of the Russian Academy of Sciences, 53, Leninskiy Prospect, Moscow, 119991, Russian Federation.

Clinic of Aesthetic Medicine, Head of the Laser Department of the Health Institute, Kharkiv, 61000, Ukraine.

出版信息

J Lasers Med Sci. 2021 Jun 9;12:e23. doi: 10.34172/jlms.2021.23. eCollection 2021.

DOI:10.34172/jlms.2021.23
PMID:34733746
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8558703/
Abstract

Surgical methods for removing eyelid nevus are associated with a risk of developing such side effects as scarring or loss of eyelashes. Although current laser modalities have shown promising results, eyelid laser surgery may cause skin discoloration and noticeable scarring. This study aims at evaluating the efficacy and safety of the dual-wavelengths copper vapor laser (CVL) treatment of eyelid intradermal nevus of Miescher (NM). We present three adult female patients with eyelid intradermal nevus treated with CVL. CVL settings were as follows: the average power of 0.6-0.8 W, under a power ratio of 3:2 at wavelengths of 511 nm and 578 nm, exposure time of 0.3 seconds, the light spot diameter of 1 mm. The dual-wavelength CVL treatment of medium- and large-sized NM provides the complete removal of eyelid dome-like NM after one and two sessions with a month interval correspondingly. The duration of skin healing accounted for two weeks. The complete removal of eyelid NM lesions without side effects demonstrates the safety and efficacy of dual-wavelengths CVL in treating such skin lesions. This laser treatment mode of benign skin neoplasms seems promising for dermatologists and cosmetologists' clinical practice.

摘要

切除眼睑痣的手术方法存在出现诸如瘢痕形成或睫毛脱落等副作用的风险。尽管目前的激光治疗方式已显示出有前景的结果,但眼睑激光手术可能会导致皮肤色素沉着和明显的瘢痕形成。本研究旨在评估双波长铜蒸气激光(CVL)治疗眼睑米舍尔真皮内痣(NM)的疗效和安全性。我们展示了3例接受CVL治疗的成年女性眼睑真皮内痣患者。CVL设置如下:平均功率0.6 - 0.8W,波长511nm和578nm时功率比为3:2,曝光时间0.3秒,光斑直径1mm。双波长CVL治疗中大型NM,分别在间隔一个月的一次和两次治疗后可完全去除眼睑穹顶状NM。皮肤愈合时间为两周。完全去除眼睑NM病变且无副作用证明了双波长CVL治疗此类皮肤病变的安全性和有效性。这种针对良性皮肤肿瘤的激光治疗模式对皮肤科医生和美容医生的临床实践似乎很有前景。

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本文引用的文献

1
Treatment of Basal Cell Cancer With a Pulsed Copper Vapor Laser: A Case Series.脉冲铜蒸气激光治疗基底细胞癌:病例系列
J Lasers Med Sci. 2019 Fall;10(4):350-354. doi: 10.15171/jlms.2019.57. Epub 2019 Oct 1.
2
Clinical and dermoscopic features of surgically treated melanocytic nevi: a retrospective study of 1046 cases.临床和皮肤镜特征的手术治疗的黑色素细胞痣:回顾性研究 1046 例。
Chin Med J (Engl). 2019 Sep 5;132(17):2027-2032. doi: 10.1097/CM9.0000000000000416.
3
Numerical Modeling and Clinical Evaluation of Pulsed Dye Laser and Copper Vapor Laser in Skin Vascular Lesions Treatment.脉冲染料激光和铜蒸气激光治疗皮肤血管病变的数值模拟与临床评估
J Lasers Med Sci. 2019 Winter;10(1):44-49. doi: 10.15171/jlms.2019.07. Epub 2018 Dec 18.
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Ocular Injury in Cosmetic Laser Treatments of the Face.面部美容激光治疗中的眼部损伤
J Clin Aesthet Dermatol. 2018 Feb;11(2):15-18. Epub 2018 Feb 1.
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Endothelial Cells Promote Pigmentation through Endothelin Receptor B Activation.内皮细胞通过激活内皮素受体B促进色素沉着。
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Laser therapy of a dermal nevus in the esthetic zone of the nasal tip: A case report and comprehensive literature review.鼻尖美学区域皮肤痣的激光治疗:一例报告及文献综述
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Treatment of eyelid nevus with CO2 laser: A double-edged sword.二氧化碳激光治疗眼睑痣:一把双刃剑。
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Optical properties of biological tissues: a review.生物组织的光学特性:综述。
Phys Med Biol. 2013 Jun 7;58(11):R37-61. doi: 10.1088/0031-9155/58/11/R37. Epub 2013 May 10.
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Ocular injury after laser hair reduction treatment to the eyebrow.激光脱毛治疗眉毛后发生的眼部损伤。
Arch Ophthalmol. 2012 Oct;130(10):1330-4. doi: 10.1001/archophthalmol.2012.1988.