School of Medicine, University of Jordan, Amman, Jordan.
the Department of Neurology, Grandview Medical Center, Birmingham, AL.
Neurologist. 2021 Nov 4;26(6):261-267. doi: 10.1097/NRL.0000000000000360.
Coronavirus disease 2019 (COVID-19) has been shown to associate with increased risk of thromboembolic events. Mechanical thrombectomy (MT) has long been used to effectively manage those with large-vessel occlusive (LVO) stroke and has similarly been implemented in the management of stroke in COVID-19 patients.
The COVID-19 pandemic took the health care sector by a storm. Thus, less is known about MT outcomes in this population and evidence suggesting poor outcomes postthrombectomy for COVID-19 patients is accumulating. We provide a narrative on some of the published studies on the outcomes of MT in COVID-19 patients with LVO between March 2020 and February 2021. A description of patient characteristics, risk factors, COVID-19 infection severity, stroke features and thrombectomy success in this population is also presented as data from several studies show that LVO in COVID-19 patients may have some distinguishing characteristics that make management more challenging.
The effect of COVID-19 on the long-term prognosis of stroke patients after thrombectomy is yet to be determined. The accumulating evidence from current studies indicates a negative impact of COVID-19 on outcomes in acute ischemic stroke patients who receive MT, irrespective of timely, successful angiographic recanalization. This review may help alert clinicians of some of the COVID-19-specific postthrombectomy challenges.
新型冠状病毒病 2019（COVID-19）已被证明与血栓栓塞事件的风险增加有关。机械血栓切除术（MT）长期以来一直用于有效治疗大血管闭塞（LVO）性中风患者，并且在 COVID-19 患者中风的治疗中也同样得到了应用。
COVID-19 大流行给医疗保健部门带来了冲击。因此，关于该人群中 MT 结果的了解较少，并且有证据表明 COVID-19 患者血栓切除术后的预后较差。我们对 2020 年 3 月至 2021 年 2 月期间发表的一些关于 LVO 型 COVID-19 患者 MT 结果的研究进行了叙述。还描述了该人群中患者特征、危险因素、COVID-19 感染严重程度、中风特征和血栓切除术成功的情况，因为一些研究的数据表明，COVID-19 患者的 LVO 可能具有一些使其治疗更具挑战性的特征。
COVID-19 对接受 MT 治疗的中风患者血栓切除术后长期预后的影响仍有待确定。目前研究中的累积证据表明，COVID-19 对接受 MT 的急性缺血性中风患者的结局有负面影响，无论其是否及时、成功地进行血管再通。本综述可能有助于提醒临床医生注意 COVID-19 特异性血栓切除术后的一些挑战。
