在中国西南部云南省汉族人群中分析的 16 个 X-STR 基因座的遗传多态性。
Genetic polymorphisms of 16 X-STR loci analyzed in the Han population of Yunnan Province, Southwest China.
机构信息
School of Forensic Medicine, Kunming Medical University, Kunming, Yunnan Province, People's Republic of China; Judicial Expertise Center of Kunming Medical University, Kunming, Yunnan Province, People's Republic of China.
School of Forensic Medicine, Kunming Medical University, Kunming, Yunnan Province, People's Republic of China.
出版信息
Leg Med (Tokyo). 2022 Feb;54:101974. doi: 10.1016/j.legalmed.2021.101974. Epub 2021 Oct 9.
To investigate the genetic diversity and forensic identification efficiency of X-chromosomal short tandem repeats (X-STRs) in the Yunnan Han population, 16 X-STRs in 415 Yunnan Han individuals (247 males and 168 females) were studied. A total of 137 alleles were detected, and all loci in the Yunnan Han population were highly polymorphic. The combined discrimination of males (PDm) and females (PDf) was 0.9999997769115 and 0.999999999999999999996, respectively. Interpopulation comparisons between the Yunnan Han population and 21 other populations showed that the evolutionary relationships between different groups with the same ethnic group or nearby geographic origins were closer. This study provides the first data on X-STR genetic polymorphisms in the Yunnan Han population and enriches the X-STR database for the Chinese Han population.
为了研究云南汉族人群 X 染色体短串联重复序列（X-STR）的遗传多样性和法医学鉴定效率，对 415 名云南汉族个体（247 名男性和 168 名女性）的 16 个 X-STR 进行了研究。共检测到 137 个等位基因，云南汉族人群所有位点均具有高度多态性。男性（PDm）和女性（PDf）的组合鉴别力分别为 0.9999997769115 和 0.999999999999999999996。云南汉族人群与 21 个其他人群的群体间比较显示，同一民族或相近地理起源的不同群体之间的进化关系更为密切。本研究提供了云南汉族人群 X-STR 遗传多态性的首批数据，丰富了中国汉族人群的 X-STR 数据库。
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