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血管内修复治疗钝性创伤性主动脉损伤与开放技术相比是否提供更好的结果?系统评价和荟萃分析。

Does Endovascular Repair for Blunt Traumatic Aortic Injuries Provide Better Outcomes Compared to Its Open Technique? A Systematic Review and Meta-analysis.

机构信息

Westchester Medical Center, Valhalla, NY.

New York Medical College, School of Medicine, Valhalla, NY.

出版信息

Surg Technol Int. 2021 Nov 4;39:283-296. doi: 10.52198/21.STI.39.CV1489.

DOI:10.52198/21.STI.39.CV1489
PMID:34736285
Abstract

INTRODUCTION

Traumatic aortic injuries are devastating events in terms of high mortality and morbidity in most survivors. We aimed to compare the outcomes of endovascular repair (ER) vs. open repair (OR) in the treatment of traumatic aortic injuries.

METHODS

PubMed, Embase, and Cochrane Library were systematically searched. Postoperative mortality was the primary endpoint. Secondary endpoints included intensive care unit (ICU) length of stay, hospital length of stay, operating time, paraplegia, stroke, acute renal failure, and reoperation rate. The Mantel-Haenszel method (random-effects model) with odds ratios and 95% confidence intervals (OR (95% CI)), and the inverse variance method with the mean difference (MD (95% CI)), were used to measure the effects of continuous and categorical variables, respectively.

RESULTS

A total of 49 studies involving 12,857 patients were included. Postoperative mortality was not significantly different between the two groups (p=0.459). Among secondary outcomes, the paraplegia rate was significantly lower after ER (p=0.032). Other secondary endpoints such as ICU length of stay (p=0.329), hospital length of stay (p=0.192), operating time (p=0.973), stroke rate (p=0.121), ARF rate (p=0.928), and reoperation rate (p=0.643) did not significantly differ between the two groups.

CONCLUSION

This meta-analysis found that ER was associated with a reduced paraplegia rate compared to OR for the management of traumatic aortic injury.

摘要

简介

在大多数幸存者中,创伤性主动脉损伤的死亡率和发病率都很高,因此这是一个毁灭性的事件。我们旨在比较血管内修复(ER)与开放修复(OR)在治疗创伤性主动脉损伤中的结果。

方法

系统地检索了 PubMed、Embase 和 Cochrane Library。术后死亡率是主要终点。次要终点包括重症监护病房(ICU)住院时间、住院时间、手术时间、截瘫、中风、急性肾功能衰竭和再次手术率。使用 Mantel-Haenszel 方法(随机效应模型)和比值比及 95%置信区间(OR(95%CI)),以及Inverse Variance 方法和平均差异(MD(95%CI))分别用于测量连续和分类变量的效果。

结果

共纳入 49 项研究,涉及 12857 名患者。两组间术后死亡率无显著差异(p=0.459)。在次要结局中,ER 后截瘫率显著降低(p=0.032)。其他次要结局,如 ICU 住院时间(p=0.329)、住院时间(p=0.192)、手术时间(p=0.973)、中风率(p=0.121)、急性肾衰率(p=0.928)和再次手术率(p=0.643)在两组间无显著差异。

结论

这项荟萃分析发现,与 OR 相比,ER 治疗创伤性主动脉损伤与截瘫率降低相关。

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