School of Chemistry and Molecular Engineering, Shanghai Key Laboratory for Urban Ecological Processes and Eco-Restoration, Shanghai Key Laboratory of Multidimensional Information Processing, Engineering Research Centre for Nanophotonics and Advanced Instrument (Ministry of Education), East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China.
School of Chemistry and Molecular Engineering, Shanghai Key Laboratory for Urban Ecological Processes and Eco-Restoration, Shanghai Key Laboratory of Multidimensional Information Processing, Engineering Research Centre for Nanophotonics and Advanced Instrument (Ministry of Education), East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China.
Talanta. 2022 Jan 15;237:122920. doi: 10.1016/j.talanta.2021.122920. Epub 2021 Oct 2.
Antibiotic residues in aquatic environments have attracted wide attention. Considering the impacts on the ecosystem and human health, it is urgent to develop a rapid method for detecting antibiotic residues in the environment. In this work, a nanoscale lanthanide metal-organic framework Eu(TATB) with a stable red luminescence in aqueous solution is synthesized by the microemulsion method. Sulfamethazine (SMZ) is frequently most used in veterinary medicine as one of sulfonamides. Eu(TATB) can be used for sensitively and rapidly specific recognition of SMZ with low detection limit (0.67 μM) and eminent recyclability. In addition, a paper-based visual system for point-of-care (POC) monitoring SMZ is devised by both using filter paper embedded with Eu(TATB) and our developed portable smartphone-involved imaging cassette. The naked eyes can observe that the red luminescence of the paper sensor gradually fades away at the presence of SMZ. This provides a reliable and effective method for on-site detection of sulfonamide antibiotics in the field of environmental monitoring.
在水环境中，抗生素残留已引起广泛关注。考虑到其对生态系统和人类健康的影响，迫切需要开发一种快速检测环境中抗生素残留的方法。在这项工作中，通过微乳液法合成了一种在水溶液中具有稳定红色发光的纳米级镧系金属有机框架 Eu(TATB)。磺胺甲噁唑（SMZ）是兽医中最常用的磺胺类药物之一。Eu(TATB)可以用于对 SMZ 进行灵敏且快速的特异性识别，检测限低（0.67 μM），且可重复使用性强。此外，通过在滤纸上嵌入 Eu(TATB)和我们开发的便携式智能手机相关成像盒，设计了一种用于即时检测（POC）监测 SMZ 的基于纸的可视化系统。肉眼可以观察到在存在 SMZ 的情况下，纸传感器的红色发光逐渐消失。这为环境监测领域中现场检测磺胺类抗生素提供了一种可靠有效的方法。
