Mengelkoch Summer, Gassen Jeff, Corrigan Emily K, Hill Sarah E
Department of Psychology, Texas Christian University, Fort Worth, TX, United States.
Pers Individ Dif. 2022 Jan;184. doi: 10.1016/j.paid.2021.111179. Epub 2021 Aug 20.
Decades of research finds associations between personality traits and health. In recent years, it has become clear that the activities of the immune system play a key role in linking these variables. In the current work, we add to this research by exploring the relationship between Big Five personality traits and (Study 1) polymorphisms known to impact cytokine release and (Study 2) immunological parameters measured (differential white blood cell counts, plasma proinflammatory cytokine levels) and (proinflammatory cytokine release by peripheral blood mononuclear cells, growth in plasma). Results provide insights into potential mechanistic drivers of the link between personality and immune function and the possibility that, in some cases, relationships between personality and immune function may be sex differentiated.
数十年的研究发现了人格特质与健康之间的关联。近年来，免疫系统的活动在连接这些变量方面起着关键作用已变得清晰。在当前的研究中，我们通过探索大五人格特质与（研究1）已知会影响细胞因子释放的多态性以及（研究2）所测量的免疫参数（白细胞分类计数、血浆促炎细胞因子水平）和（外周血单核细胞的促炎细胞因子释放、血浆中的生长情况）之间的关系，为这项研究增添了内容。研究结果为性格与免疫功能之间联系的潜在机制驱动因素以及在某些情况下性格与免疫功能之间的关系可能存在性别差异的可能性提供了见解。
