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镁紊乱可导致焦磷酸钙沉积病:一例报告及文献综述。

Magnesium disorders can cause calcium pyrophosphate deposition disease: A case report and literature review.

作者信息

Joshi Akanksha, Siva Chokkalingam

机构信息

Division of Rheumatology, Department of Internal Medicine, University of Missouri, Columbia, MO, USA.

出版信息

Eur J Rheumatol. 2018 Mar;5(1):53-57. doi: 10.5152/eurjrheum.2017.16116. Epub 2017 Aug 29.

DOI:10.5152/eurjrheum.2017.16116
PMID:29657876
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5895153/
Abstract

Calcium pyrophosphate deposition (CPPD) disease, also known as pseudogout, is one of the most common forms of inflammatory arthritis. A variety of comorbidities and metabolic conditions have been recognized to predispose to CPPD. We describe here a patient with chronic CPP arthritis due to hypomagnesemia, which is one of the metabolic etiologies associated with CPPD, especially in younger patients. We also performed a literature search and reviewed all reported cases of CPPD disease associated with hypomagnesemia. All cases of hypomagnesemia and its etiologies leading to CPP arthropathy identified in the literature by this systematic search are summarized in this paper.

摘要

焦磷酸钙沉积(CPPD)病,又称假痛风,是最常见的炎性关节炎形式之一。多种合并症和代谢状况已被认为易引发CPPD。我们在此描述一名因低镁血症导致慢性CPP关节炎的患者,低镁血症是与CPPD相关的代谢病因之一,尤其在年轻患者中。我们还进行了文献检索,并回顾了所有报道的与低镁血症相关的CPPD病病例。本文总结了通过该系统检索在文献中确定的所有低镁血症病例及其导致CPP关节病的病因。

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[Chondrocalcinosis: idiopathic or manifestation of rare metabolic diseases?].[软骨钙质沉着症:特发性还是罕见代谢性疾病的表现?]
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本文引用的文献

1
Effect of parathyroid hormone on serum magnesium levels: the neglected relationship in hemodialysis patients with secondary hyperparathyroidism.甲状旁腺激素对血清镁水平的影响:血液透析合并继发性甲状旁腺功能亢进患者中被忽视的关系
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Chondrocalcinosis related to familial hypomagnesemia with hypercalciuria and nephrocalcinosis.与家族性低镁血症伴高钙尿症和肾钙质沉着症相关的软骨钙质沉着症。
J Pediatr Endocrinol Metab. 2015 May;28(5-6):713-6. doi: 10.1515/jpem-2013-0254.
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Methotrexate in chronic-recurrent calcium pyrophosphate deposition disease: no significant effect in a randomized crossover trial.甲氨蝶呤治疗慢性复发性焦磷酸钙沉积病:一项随机交叉试验显示无显著疗效
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4
Efficacy of anakinra in calcium pyrophosphate crystal-induced arthritis: a report of 16 cases and review of the literature.焦磷酸钙晶体诱导关节炎中阿那白滞素的疗效:16 例报告及文献复习。
Joint Bone Spine. 2013 Mar;80(2):178-82. doi: 10.1016/j.jbspin.2012.07.018. Epub 2012 Sep 28.
5
Chronic calcium pyrophosphate crystal inflammatory arthritis induced by extreme hypomagnesemia in short bowel syndrome.短肠综合征引起的严重低镁血症致慢性焦磷酸钙晶体炎症性关节炎。
BMC Gastroenterol. 2012 Sep 22;12:129. doi: 10.1186/1471-230X-12-129.
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[Chondrocalcinosis and hypomagnesemia: clinical and radiological progression].
Reumatol Clin. 2008 Jan;4(1):37-9. doi: 10.1016/S1699-258X(08)71794-7. Epub 2008 Oct 28.
7
European League Against Rheumatism recommendations for calcium pyrophosphate deposition. Part I: terminology and diagnosis.欧洲抗风湿病联盟焦磷酸钙沉积症建议。第一部分:术语和诊断。
Ann Rheum Dis. 2011 Apr;70(4):563-70. doi: 10.1136/ard.2010.139105. Epub 2011 Jan 7.
8
Pseudoneuropathic CPPD arthropathy: magnesium matters.
Rheumatology (Oxford). 2008 Apr;47(4):551-2. doi: 10.1093/rheumatology/ken016. Epub 2008 Feb 12.
9
Transcriptional and functional analyses of SLC12A3 mutations: new clues for the pathogenesis of Gitelman syndrome.SLC12A3 突变的转录和功能分析:吉特曼综合征发病机制的新线索
J Am Soc Nephrol. 2007 Apr;18(4):1271-83. doi: 10.1681/ASN.2006101095. Epub 2007 Feb 28.
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Methotrexate as an alternative therapy for chronic calcium pyrophosphate deposition disease: an exploratory analysis.甲氨蝶呤作为慢性焦磷酸钙沉积病的替代疗法:一项探索性分析。
Arthritis Rheum. 2007 Feb;56(2):688-92. doi: 10.1002/art.22389.