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胰十二指肠切除术治疗沟部胰腺炎:一例病例报告及文献综述

Pancreatoduodenectomy for groove pancreatitis: A case report and literature review.

作者信息

Bacalbasa Nicolae, Balescu Irina, Dima Simona, Popescu Irinel

机构信息

Department of Obstetrics and Gynecology, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.

Department of Visceral Surgery, Center of Excellence in Translational Medicine, 'Fundeni' Clinical Institute, 022328 Bucharest, Romania.

出版信息

Exp Ther Med. 2021 Dec;22(6):1455. doi: 10.3892/etm.2021.10890. Epub 2021 Oct 18.

Abstract

Groove pancreatitis represents a rare pathological condition which is usually associated with chronic alcohol intake. However, the differential diagnosis between groove pancreatitis and groove pancreatic carcinoma is difficult to establish pre-operatively. In this respect, a significant number of cases are treated as malignant conditions, with the final diagnosis of benign disease being established post-operatively. The present study describes the case of a 46-year-old male who was diagnosed with groove pancreatitis. Due to the uncertainty of the pre-operative diagnosis, the patient was subjected to radical surgery consisting of pancreatoduodenectomy. The final histopathological diagnosis confirmed the presence of groove pancreatitis. Moreover, it excluded the possibility of an association with any element of malignancy and provided the effective management of the disease, all the symptoms being significantly alleviated at the 3-month follow-up. In addition, the present study also provides a brief summary and discussion of the disease and associated treatment options. On the whole, as demonstrated herein, pancreatoduodenectomy appears to be a safe and effective method for the treatment of groove pancreatitis, being associated with a significant improvement in the quality of life of the patient; moreover, it represents the sole method which can exclude the diagnosis of malignancy.

摘要

沟部胰腺炎是一种罕见的病理状况,通常与长期饮酒有关。然而,术前很难鉴别沟部胰腺炎与沟部胰腺癌。在这方面,相当多的病例被当作恶性疾病治疗,最终在术后才确诊为良性疾病。本研究描述了一名46岁男性被诊断为沟部胰腺炎的病例。由于术前诊断不明确,该患者接受了包括胰十二指肠切除术在内的根治性手术。最终的组织病理学诊断证实为沟部胰腺炎。此外,排除了与任何恶性因素相关的可能性,并对该疾病进行了有效治疗,在3个月的随访中所有症状均显著缓解。此外,本研究还对该疾病及相关治疗方案进行了简要总结和讨论。总体而言,如本文所示,胰十二指肠切除术似乎是治疗沟部胰腺炎的一种安全有效的方法,可显著改善患者的生活质量;此外,它是唯一能排除恶性诊断的方法。

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