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前交叉韧带重建后,各种患者报告的分类标准中早期膝关节骨关节炎疾病的患病率。

Prevalence of Early Knee Osteoarthritis Illness Among Various Patient-Reported Classification Criteria After Anterior Cruciate Ligament Reconstruction.

机构信息

Michigan State University, East Lansing.

Creighton University, Omaha, Nebraska.

出版信息

Arthritis Care Res (Hoboken). 2022 Mar;74(3):377-385. doi: 10.1002/acr.24809. Epub 2022 Feb 11.

Abstract

OBJECTIVE

To compare the prevalence of participants meeting different patient-reported criteria for early osteoarthritis (OA) illness after anterior cruciate ligament reconstruction (ACLR).

METHODS

Participants completed the Knee Injury and Osteoarthritis Outcomes Score (KOOS) at a single time point 5.0-7.9 months post-ACLR. We used established KOOS subscale criteria (i.e., Luyten original and Englund original) to define patient-reported early OA illness. A two-by-two contingency table and McNemar's test were used to compare the prevalence of participants who met the Luyten original versus Englund original KOOS criteria for early OA illness. These analyses were repeated using KOOS subscale thresholds based on established population-specific patient acceptable symptom state (PASS) within the Luyten and Englund KOOS criteria (i.e., Luyten PASS and Englund PASS).

RESULTS

A greater prevalence of participants with ACLR met the Luyten original criteria (n = 165 [54%]) compared to those who met the Englund original criteria (n = 128 [42%]; χ  = 19.3, P < 0.001). When using the KOOS subscale PASS as thresholds, a significantly greater prevalence of participants with ACLR met the Luyten PASS criteria (n = 133 [43%]) compared to those who met the Englund PASS criteria (n = 85 [28%]; χ  = 48.0, P < 0.001). When combining the Luyten and Englund KOOS criteria and using the original/PASS subscale thresholds, respectively, 40%/57% of participants met neither, 24%/15% met only 1, and 36%/28% met both KOOS criteria.

CONCLUSION

Regardless of the classification criteria used to define early OA illness, it is concerning that 28-54% of patients report considerable symptoms ~6 months post-ACLR. Our findings will improve the classification criteria to define early OA illness, which may raise awareness for the need of population-specific criteria.

摘要

目的

比较前交叉韧带重建(ACLR)后 5.0-7.9 个月时,符合不同患者报告的早期骨关节炎(OA)疾病标准的参与者的患病率。

方法

参与者在单次时间点完成膝关节损伤和骨关节炎结果评分(KOOS)。我们使用既定的 KOOS 亚量表标准(即 Luyten 原始和 Englund 原始)来定义患者报告的早期 OA 疾病。使用两乘两列联表和 McNemar 检验比较符合 Luyten 原始和 Englund 原始 KOOS 早期 OA 疾病标准的参与者的患病率。使用基于 Luyten 和 Englund KOOS 标准中既定人群可接受症状状态(PASS)的 KOOS 亚量表阈值(即 Luyten PASS 和 Englund PASS)重复这些分析。

结果

更多的 ACLR 参与者符合 Luyten 原始标准(n=165 [54%]),而符合 Englund 原始标准的参与者较少(n=128 [42%];χ²=19.3,P<0.001)。当使用 KOOS 亚量表 PASS 作为阈值时,更多的 ACLR 参与者符合 Luyten PASS 标准(n=133 [43%]),而符合 Englund PASS 标准的参与者较少(n=85 [28%];χ²=48.0,P<0.001)。当结合 Luyten 和 Englund KOOS 标准并分别使用原始/PASS 亚量表阈值时,40%/57%的参与者不符合任何标准,24%/15%的参与者仅符合 1 个标准,36%/28%的参与者符合这两个 KOOS 标准。

结论

无论使用何种分类标准来定义早期 OA 疾病,都令人担忧的是,28-54%的患者在 ACLR 后约 6 个月报告有相当多的症状。我们的研究结果将改善定义早期 OA 疾病的分类标准,这可能会提高对制定特定人群标准的认识。

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