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[病证结合药理学:中药药理学的策略与方法]

[Pharmacology of combination of disease and syndrome:strategies and methods of pharmacology of Chinese medicine].

作者信息

Ren Jun-Guo, Liu Jian-Xun, Wei Jia-Hui

机构信息

Beijing Key Laboratory of Pharmacology of Traditional Chinese Medicine, Institute of Basic Medicine,Xiyuan Hospital, China Academy of Chinese Medical Sciences Beijing 100091, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2021 Oct;46(19):4922-4929. doi: 10.19540/j.cnki.cjcmm.20210702.701.

Abstract

The pharmacology of Chinese medicine is an academic discipline that studies the interaction between Chinese medicine and organism(including pathogens) by modern science and technology under the guidance of traditional Chinese medicine(TCM) theories. However, the pharmacology of Chinese medicine is mainly guided by the theories, techniques, and methods of modern medicine in the development, and TCM theories have been ignored to a certain extent, which does not conform to the action characteristics of Chinese medicine in essence. Since systematic research ideas, strategies, methods, and technologies that conform to the characteristics of TCM have not been established, it is unable to reveal the scientific connotation of TCM in the prevention and treatment of diseases. Therefore, according to the trend of the modern development of TCM and the research status of pharmacology of Chinese medicine, this study put forward the concept of pharmacology of combination of disease and syndrome and expounded the relevant background, content, methods, and significance of this concept. It is expected to improve the standardization of pharmacology of combination of disease and syndrome, guide the safe medication, provide new references for the scientific development of pharmacology of Chinese medicine, and promote the development of the modernization of Chinese medicine.

摘要

中药药理学是在中医药理论指导下,运用现代科学技术研究中药与机体(包括病原体)相互作用规律的一门学科。然而,中药药理学在发展过程中主要以现代医学的理论、技术和方法为指导,中医药理论在一定程度上被忽视,这在本质上不符合中药的作用特点。由于尚未建立起符合中医药特点的系统研究思路、策略、方法和技术,无法揭示中医药在防治疾病中的科学内涵。因此,根据中医药现代发展趋势及中药药理学研究现状,本研究提出病证结合药理学的概念,并阐述了这一概念的相关背景、内容、方法及意义。期望提高病证结合药理学的规范化水平,指导安全用药,为中药药理学的科学发展提供新的参考,推动中医药现代化发展。

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