Flint A, Cookingham C
Acta Cytol. 1987 May-Jun;31(3):325-9.
The papillary variant of renal-cell carcinoma is characterized by distinctive histologic, clinical and angiographic features. A study was undertaken to delineate the cytologic features of this tumor as it is encountered in cellular samples. Cytologic specimens containing tumor cells from eight patients who underwent resection for papillary renal-cell carcinoma were examined and compared to corresponding cytologic samples obtained from ten other patients who had nonpapillary renal-cell carcinoma. The cytologic appearance of papillary renal-cell carcinoma, which is deceptively benign, is marked by distinctive papillary structures that often resemble branched chains. The cells are usually small and contain uniform nuclei; numerous macrophages with foamy cytoplasm are often found in the background. These cytologic features were not observed in the cellular specimens from the nonpapillary renal carcinomas. We conclude that papillary renal-cell carcinoma can be confidently recognized in cytologic specimens.
肾细胞癌的乳头状变异型具有独特的组织学、临床和血管造影特征。本研究旨在描绘该肿瘤在细胞样本中的细胞学特征。对8例接受乳头状肾细胞癌切除术患者的含肿瘤细胞的细胞学标本进行了检查，并与另外10例非乳头状肾细胞癌患者的相应细胞学样本进行了比较。乳头状肾细胞癌的细胞学表现看似良性，其特征为独特的乳头状结构，常类似分支链。细胞通常较小，核均匀；背景中常可见大量胞质呈泡沫状的巨噬细胞。非乳头状肾癌的细胞标本未观察到这些细胞学特征。我们得出结论，乳头状肾细胞癌在细胞学标本中可得到可靠识别。
