University of Cambridge Foundation Trust, Addenbrooke's Hospital, Cambridge, UK.
University of Birmingham, Medical School, Birmingham, UK.
Otol Neurotol. 2022 Jan 1;43(1):e1-e13. doi: 10.1097/MAO.0000000000003353.
To determine outcomes following cochlear implantation (CI) in children with autism spectrum disorder (ASD).
MEDLINE, Embase, Web of science, Cochrane Library, and Clinicaltrial.gov.
The review was performed according to the PRISMA statement. Primary outcomes measures were changes in speech perception and speech production scores. Secondary outcome measures included communication mode, device use, parental recommendation of implant, postoperative hyperacusis, and quality of life measures. Pooled analysis of outcomes was performed if possible.
Twenty-four studies reported on 159 children with ASD. There were improvements in speech perception in 78% of cases and in speech expression in 63% of cases, though the extent of this improvement was variable. Seventy-four percent of children with ASD and CI are nonoral communicators. Intermittent/nonuse rate was 31%. Hearing outcomes are worse compared to children with other disabilities. The vast majority of parents would recommend CI based on their experiences.
Outcome in children with ASD and CI are highly variable and significantly poorer compared to non-ASD children. Despite this, most parents report positive experiences and the evidence supports the use of CI in children with ASD.
确定自闭症谱系障碍（ASD）儿童接受人工耳蜗植入（CI）后的结果。
MEDLINE、Embase、Web of science、Cochrane Library 和 Clinicaltrial.gov。
本综述按照 PRISMA 声明进行。主要结局指标为言语感知和言语产生评分的变化。次要结局指标包括沟通模式、设备使用、父母对植入的推荐、术后听觉过敏和生活质量测量。如果可能，对结果进行了汇总分析。
24 项研究报告了 159 名 ASD 儿童。78%的病例言语感知能力有改善，63%的病例言语表达能力有改善，但改善程度各不相同。74%的 ASD 和 CI 儿童是非口语沟通者。间歇性/非使用者比例为 31%。与其他残疾儿童相比，听力结果更差。绝大多数父母会根据自己的经验推荐 CI。
ASD 和 CI 儿童的结果差异很大，明显比非 ASD 儿童差。尽管如此，大多数父母报告了积极的体验，并且证据支持在 ASD 儿童中使用 CI。
