Universidade de Brasília (UnB), Programa de Pós-Graduação em Ciências da Saúde, Brasília, DF, Brazil.
Instituto René Rachou - Fiocruz Minas, FESF-TECH Bahia e Grupo de pesquisa em Políticas de Saúde e Proteção Social, Belo Horizonte, MG, Brazil.
Braz J Otorhinolaryngol. 2021 Sep-Oct;87(5):601-619. doi: 10.1016/j.bjorl.2020.11.020. Epub 2021 Jan 2.
In cases of autism spectrum disorders with severe to profound hearing loss, cochlear implant is a therapeutic option.
To identify evidence in the scientific literature that the cochlear implant brings benefits to people with autism spectrum disorders with associated hearing loss.
Systematic review of the literature based on the criteria recommended by PRISMA. The population, intervention, comparison, outcomes, study design, PICOS strategy, was used to define the eligibility criteria. The studies that met the inclusion criteria for this second stage were included in a qualitative synthesis. Each type of study was analyzed according to the Joanna Briggs Institute's risk of bias assessment through the critical checklist for cohort studies, prevalence studies and critical criteria and case reports.
Four hundred and eighty-four articles were found in eight databases and 100 in the gray literature, mentioning the relationship between cochlear implants in patients with autism spectrum disorder and hearing loss. Twelve articles were read in full and 7 were selected for qualitative analysis in this systematic review. All seven articles were analyzed on the critical evaluation checklist. Four articles had a low risk of bias and three articles had a moderate risk of bias. In this study, were included 66 patients with autism spectrum disorder and hearing loss who received cochlear implant.
This systematic review indicates that a cochlear implant can bring benefits to autism spectrum disorder patients with associated deafness.
对于伴有中重度至极重度听力损失的自闭症谱系障碍患者，人工耳蜗植入是一种治疗选择。
在科学文献中识别人工耳蜗植入对伴有相关听力损失的自闭症谱系障碍患者带来益处的证据。
根据 PRISMA 推荐的标准进行系统文献回顾。使用人群、干预、比较、结局、研究设计、PICOS 策略来定义纳入标准。符合第二阶段纳入标准的研究被纳入定性综合分析。根据乔安娜·布里格斯研究所（Joanna Briggs Institute）对队列研究、患病率研究和关键标准和病例报告的批判性检查表，对每种类型的研究进行分析。
在八个数据库中发现了 484 篇文章和 100 篇灰色文献，提到了自闭症谱系障碍患者人工耳蜗植入与听力损失之间的关系。全文阅读了 12 篇文章，并在这项系统评价中选择了 7 篇进行定性分析。这 7 篇文章都在批判性评估检查表上进行了分析。四篇文章的偏倚风险较低，三篇文章的偏倚风险为中度。在这项研究中，纳入了 66 名接受人工耳蜗植入的伴有听力损失的自闭症谱系障碍患者。
这项系统评价表明，人工耳蜗植入可以为伴有相关耳聋的自闭症谱系障碍患者带来益处。
