Harvard Medical School, Joslin Diabetes Center, 1 Joslin Place, Boston, MA 02215, USA.
Cell Stem Cell. 2021 Nov 4;28(11):1889-1890. doi: 10.1016/j.stem.2021.10.005.
In this issue of Cell Stem Cell, Gribben et al. (2021), using improved lineage-tracing mice and longer chase times, have provided clear evidence of new islet cells forming from the pancreatic ducts in adult mice. Perhaps these data will finally put to rest the controversy over beta cell neogenesis in the adult.
在本期《Cell Stem Cell》杂志中,Gribben 等人(2021)使用改良的谱系追踪小鼠和更长的追踪时间,提供了明确的证据表明成年小鼠的胰岛细胞可由胰腺导管生成。也许这些数据最终将平息关于成年个体中β细胞新生的争议。