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印度东部一家微生物实验室中各类产品无菌检测的重要性及结果

Importance and results of sterility testing of various products in a microbiology laboratory of eastern India.

作者信息

Mukherjee Satyam, Mukherjee Sukdev, Mahto Rajkumar, Basu Debabrata, Javed Rizwan, Goel Gaurav, Bhattacharya Sanjay, Basu Sabita, Chandy Mammen

机构信息

Department of Microbiology, Tata Medical Center, Kolkata, India.

Central Sterile Supply Department, Tata Medical Center, Kolkata, India.

出版信息

Indian J Med Microbiol. 2022 Jan-Mar;40(1):138-140. doi: 10.1016/j.ijmmb.2021.10.008. Epub 2021 Nov 3.

DOI:10.1016/j.ijmmb.2021.10.008
PMID:34740414
Abstract

Components of blood products from Blood bank, stem cells products from Haemotapoietic Stem Cell Transplant unit, CSSD (Central Sterile Supply Department) items, and pharrrmaceutical products, were sterility tested by liquid culture. 2.91% of the total 3122 samples sent for sterility testing from various departments were positive (i.e. showing contamination). CSSD products showed no contamination (0/37); products from blood bank and bone marrow transplant unit showed a contamination rate of 2.03% (47/2307) and 4.64% (31/667) respectively. The average cost of sterility test was Rs. 302 (INR). Sterility test requires stringent aseptic precautions which is resource intensive.

摘要

血库的血液制品成分、造血干细胞移植单位的干细胞制品、中央无菌供应部(CSSD)的物品以及药品,均通过液体培养进行无菌检测。从各部门送去进行无菌检测的3122个样本中,有2.91%呈阳性(即显示有污染)。CSSD的产品未显示污染(0/37);血库和骨髓移植单位的产品污染率分别为2.03%(47/2307)和4.64%(31/667)。无菌检测的平均成本为302卢比(印度卢比)。无菌检测需要严格的无菌预防措施,这需要大量资源。

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