一名患有21号染色体结构环的儿童的急性淋巴细胞白血病。
Acute lymphoblastic leukemia in a child with constitutional ring chromosome 21.
作者信息
Falchi A M, Orofino M G, Nucaro A L, De Virgiliis S, Cao A
出版信息
Cancer Genet Cytogenet. 1987 Aug;27(2):219-24. doi: 10.1016/0165-4608(87)90003-3.
PMID:3474055
Abstract
This report describes a case of acute lymphoblastic leukemia with non-B, non-T, common acute lymphocytic leukemia antigen-positive blasts in a 13-year-old child with constitutional ring chromosome #21. Because ring chromosome #21 is a rare chromosomal disorder, it is likely that the leukemia transformation is related to the chromosomal anomaly.
摘要
本报告描述了一名13岁患有先天性21号环状染色体的儿童，其急性淋巴细胞白血病的原始细胞为非B、非T、常见急性淋巴细胞白血病抗原阳性。由于21号环状染色体是一种罕见的染色体疾病，白血病转化可能与染色体异常有关。
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