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比较 Halcyon 和 Synergy Agility 系统用于切线野全乳腺照射的滑动窗口和场中野技术。

Comparison of sliding window and field-in-field techniques for tangential whole breast irradiation using the Halcyon and Synergy Agility systems.

机构信息

Department of Radiation Oncology, University of Wuerzburg, Wuerzburg, Germany.

出版信息

Radiat Oncol. 2021 Nov 6;16(1):213. doi: 10.1186/s13014-021-01942-y.

DOI:10.1186/s13014-021-01942-y
PMID:34742291
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8571882/
Abstract

BACKGROUND

To implement a tangential treatment technique for whole breast irradiation using the Varian Halcyon and to compare it with Elekta Synergy Agility plans.

METHODS

For 20 patients two comparable treatment plans with respect to dose coverage and normal tissue sparing were generated. Tangential field-in-field treatment plans (Pinnacle/Synergy) were replanned using the sliding window technique (Eclipse/Halcyon). Plan specific QA was performed using the portal Dosimetry and the ArcCHECK phantom. Imaging and treatment dose were evaluated for treatment delivery on both systems using a modified CIRS Phantom.

RESULTS

The mean number of monitor units for a fraction dose of 2.67 Gy was 515 MUs and 260 MUs for Halcyon and Synergy Agility plans, respectively. The homogeneity index and dose coverage were similar for both treatment units. The plan specific QA showed good agreement between measured and calculated plans. All Halcyon plans passed portal dosimetry QA (3%/2 mm) with 100% points passing and ArcCheck QA (3%/2 mm) with 99.5%. Measurement of the cumulated treatment and imaging dose with the CIRS phantom resulted in lower dose to the contralateral breast for the Halcyon plans.

CONCLUSIONS

For the Varian Halcyon a plan quality similar to the Elekta Synergy device was achieved. For the Halcyon plans the dose contribution from the treatment fields to the contralateral breast was even lower due to less interleaf transmission of the Halcyon MLC and a lower contribution of scattered dose from the collimator system.

摘要

背景

为了实现瓦里安 Halcyon 全乳照射的切线治疗技术,并将其与 Elekta Synergy Agility 计划进行比较。

方法

对 20 例患者进行了两种可比的治疗计划,以实现剂量覆盖和正常组织保护。使用滑动窗口技术(Eclipse/Halcyon)对切线场内场治疗计划(Pinnacle/Synergy)进行了重新规划。使用门户剂量学和 ArcCHECK 体模进行了特定于计划的 QA。使用改良的 CIRS 体模评估了两种系统上的治疗剂量分布和治疗交付。

结果

单次剂量 2.67 Gy 的平均 MU 数分别为 Halcyon 和 Synergy Agility 计划的 515 MU 和 260 MU。两个治疗单元的均匀性指数和剂量覆盖相似。计划特异性 QA 显示实测计划与计算计划之间具有良好的一致性。所有 Halcyon 计划均通过了门户剂量学 QA(3%/2mm),100%点通过,ArcCheck QA(3%/2mm)通过了 99.5%。使用 CIRS 体模测量累积治疗和成像剂量,结果表明 Halcyon 计划对健侧乳房的剂量更低。

结论

对于瓦里安 Halcyon,实现了与 Elekta Synergy 设备相似的计划质量。对于 Halcyon 计划,由于 Halcyon MLC 的叶片间传输更少,以及准直器系统散射剂量的贡献更低,治疗野对健侧乳房的剂量贡献甚至更低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fbd/8571882/39f428dcc049/13014_2021_1942_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fbd/8571882/f3646caec743/13014_2021_1942_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fbd/8571882/39f428dcc049/13014_2021_1942_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fbd/8571882/f3646caec743/13014_2021_1942_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fbd/8571882/39f428dcc049/13014_2021_1942_Fig2_HTML.jpg

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本文引用的文献

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Adv Radiat Oncol. 2019 Aug 21;5(1):120-126. doi: 10.1016/j.adro.2019.07.011. eCollection 2020 Jan-Feb.
2
Dosimetric Characterization of the Dual Layer MLC System for an O-Ring Linear Accelerator.用于 O 形环直线加速器的双层多叶准直器的剂量学特性。
Technol Cancer Res Treat. 2019 Jan-Dec;18:1533033819883641. doi: 10.1177/1533033819883641.
3
用于分段式乳腺癌放射治疗的 halcyon 环形传输系统的基准测试:快速推进试验的验证和临床实施。
J Appl Clin Med Phys. 2023 Sep;24(9):e14047. doi: 10.1002/acm2.14047. Epub 2023 May 23.
4
Independent monitor unit verification for dynamic flattened beam plans on the Halcyon linac.独立监测单位验证调强适形动态治疗计划在 Halcyon 直线加速器上的应用。
J Appl Clin Med Phys. 2023 Jan;24(1):e13807. doi: 10.1002/acm2.13807. Epub 2022 Oct 20.
Initial Clinical Experience Treating Patients with Breast Cancer on a 6-MV Flattening-Filter-Free O-Ring Linear Accelerator.
使用6兆伏无均整器O型环直线加速器治疗乳腺癌患者的初步临床经验
Adv Radiat Oncol. 2019 Jun 8;4(4):571-578. doi: 10.1016/j.adro.2019.05.006. eCollection 2019 Oct-Dec.
4
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J Appl Clin Med Phys. 2019 Nov;20(11):14-26. doi: 10.1002/acm2.12722. Epub 2019 Oct 16.
5
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Cureus. 2018 Oct 29;10(10):e3510. doi: 10.7759/cureus.3510.
8
Interdisciplinary Screening, Diagnosis, Therapy and Follow-up of Breast Cancer. Guideline of the DGGG and the DKG (S3-Level, AWMF Registry Number 032/045OL, December 2017) - Part 2 with Recommendations for the Therapy of Primary, Recurrent and Advanced Breast Cancer.乳腺癌的多学科筛查、诊断、治疗及随访。德国妇科和产科学会(DGGG)与德国癌症协会(DKG)指南(S3级,德国医学科学信息平台AWMF注册号032/045OL,2017年12月) - 第2部分:原发性、复发性和晚期乳腺癌治疗建议
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10
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Radiother Oncol. 2016 Jan;118(1):205-8. doi: 10.1016/j.radonc.2015.12.027. Epub 2016 Jan 18.