Zhou Qiong, Wang Qi, Li Yongwu, Shen Chong, Sun Xiaonan
Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, 310000, China.
Sci Rep. 2024 Dec 28;14(1):30862. doi: 10.1038/s41598-024-81310-4.
Recently, neoadjuvant short-course radiation therapy (SCRT) has emerged as a valid treatment option for patients with locally advanced rectal cancer (LARC). We assessed SCRT plans using volumetric-modulated arc therapy (VMAT) with Halcyon and Infinity medical linear accelerators (Linacs) and compared the plan quality and delivery efficiency across all cases. Thirty patients who underwent preoperative SCRT for LARC at the hospital were randomly selected. Treatment plans were designed using the Halcyon and Infinity linac platforms, generating Halcyon VMAT plans (Group H) and Infinity VMAT plans (Group I). The target coverage, organ at risk (OAR) dose distribution, number of monitor units, treatment delivery time, and planning complexity of the two groups were compared and analyzed. Plan quality assurance was performed on the ArcCheck phantom. The overall plan quality regarding target volume and OARs was comparable for plans delivered on Halcyon and Infinity Agility machines, with each platform having advantages. Therefore, both radiotherapy platforms are very good options when selecting which technique to use in the clinic.
最近，新辅助短程放疗（SCRT）已成为局部晚期直肠癌（LARC）患者的一种有效治疗选择。我们使用配备Halcyon和Infinity医用直线加速器（直线加速器）的容积调强弧形放疗（VMAT）评估了SCRT计划，并比较了所有病例的计划质量和实施效率。随机选择了30例在该医院接受LARC术前SCRT的患者。使用Halcyon和Infinity直线加速器平台设计治疗计划，生成Halcyon VMAT计划（H组）和Infinity VMAT计划（I组）。比较并分析了两组的靶区覆盖情况、危及器官（OAR）剂量分布、监测单位数量、治疗实施时间和计划复杂性。在ArcCheck模体上进行计划质量保证。在Halcyon和Infinity Agility机器上实施的计划，其关于靶区体积和OARs的总体计划质量相当，每个平台都有优势。因此，在临床选择使用哪种技术时，这两种放疗平台都是非常好的选择。
