Watkins W B, Moore L G
J Reprod Fertil. 1987 May;80(1):105-12. doi: 10.1530/jrf.0.0800105.
Systemic intravenous infusion of physiological concentrations of PGF-2 alpha and its major metabolite, 13, 14-dihydro-15-keto-PGF-2 alpha (PGFM) into non-pregnant ewes possessing a corpus luteum induced the release of oxytocin-neurophysin. These results suggest that, during luteolysis, endogenous release of uterine PGF-2 alpha would be able to stimulate the release of ovarian oxytocin and oxytocin-neurophysin from the ovary.
向有黄体的未孕母羊全身静脉输注生理浓度的前列腺素F-2α及其主要代谢产物13,14-二氢-15-酮-前列腺素F-2α(PGFM),可诱导催产素-神经垂体素的释放。这些结果表明,在黄体溶解过程中,子宫内源性前列腺素F-2α的释放能够刺激卵巢催产素和催产素-神经垂体素从卵巢释放。