Mizoguchi Takeru, Yoshida Kenji, Mamou Jonathan, Ketterling Jeffrey A, Yamaguchi Tadashi
Graduate School of Science and Engineering, Chiba University, Yayoicho, Inage, Chiba 263-8522, Japan.
Center for Frontier Medical Engineering, Chiba University, Yayoicho, Inage, Chiba 263-8522, Japan.
Jpn J Appl Phys (2008). 2020 Jul;59(SK). doi: 10.35848/1347-4065/ab8bcb. Epub 2020 May 7.
Clinical ultrasound is widely used for quantitative diagnosis. To clarify the relationship between anatomical and acoustic properties, high resolution imaging using high-frequency ultrasound (HFU) is required. However, when tissue properties are evaluated using HFU, the depth of field (DOF) is limited. To overcome this problem, an annular array transducer, which has a simple structure and produces high-quality images, is applied to HFU measurement. In previous phantom experiments, we demonstrated that the HFU annular array extends the DOF compared to that of a single-element transducer for quantitative ultrasound (QUS) analysis. Here, we extend that work by applying QUS methods to an ex vivo rat liver. The present study demonstrates that an annular array extends the region and improves the resolution for tissue characterization for an excised healthy rat liver. Amplitude envelope statistics and spectral-based analysis are used as QUS methods.
临床超声广泛用于定量诊断。为了阐明解剖学特性与声学特性之间的关系，需要使用高频超声（HFU）进行高分辨率成像。然而，当使用HFU评估组织特性时，景深（DOF）是有限的。为了克服这个问题，一种结构简单且能产生高质量图像的环形阵列换能器被应用于HFU测量。在之前的体模实验中，我们证明了与用于定量超声（QUS）分析的单元素换能器相比，HFU环形阵列扩展了景深。在此，我们通过将QUS方法应用于离体大鼠肝脏来扩展这项工作。本研究表明，环形阵列扩展了区域并提高了对切除的健康大鼠肝脏进行组织表征的分辨率。幅度包络统计和基于频谱的分析被用作QUS方法。
