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Editorial: Dynamic Biomarkers of Response to Anti-Immune Checkpoint Inhibitors in Cancer.

作者信息

Dermime Said, Merhi Maysaloun, Merghoub Taha

机构信息

National Center for Cancer Care and Research, Hamad Medical Corporation, Doha, Qatar.

Translational Cancer Research Facility, Translational Research Institute, Hamad Medical Corporation, Doha, Qatar.

出版信息

Front Immunol. 2021 Oct 21;12:781872. doi: 10.3389/fimmu.2021.781872. eCollection 2021.

DOI:10.3389/fimmu.2021.781872
PMID:34745152
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8567164/
Abstract
摘要

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本文引用的文献

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Emerging dynamics pathways of response and resistance to PD-1 and CTLA-4 blockade: tackling uncertainty by confronting complexity.PD-1 和 CTLA-4 阻断治疗反应和耐药的新兴动力学途径：通过应对复杂性来解决不确定性。
J Exp Clin Cancer Res. 2021 Feb 18;40(1):74. doi: 10.1186/s13046-021-01872-3.
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Persistent anti-NY-ESO-1-specific T cells and expression of differential biomarkers in a patient with metastatic gastric cancer benefiting from combined radioimmunotherapy treatment: a case report.一名转移性胃癌患者接受联合放射免疫治疗后获益，其体内存在持续的抗 NY-ESO-1 特异性 T 细胞和表达差异生物标志物：一例报告。
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Squamous Cell Carcinomas of the Head and Neck Cancer Response to Programmed Cell Death Protein-1 Targeting and Differential Expression of Immunological Markers: A Case Report.头颈部鳞状细胞癌对程序性细胞死亡蛋白-1 靶向治疗的反应及免疫标志物的差异表达：一例报告。
Front Immunol. 2018 Jul 30;9:1769. doi: 10.3389/fimmu.2018.01769. eCollection 2018.
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Overall Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma.纳武利尤单抗联合伊匹木单抗治疗晚期黑色素瘤的总生存期
N Engl J Med. 2017 Oct 5;377(14):1345-1356. doi: 10.1056/NEJMoa1709684. Epub 2017 Sep 11.
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Pembrolizumab versus Ipilimumab in Advanced Melanoma.帕博利珠单抗对比伊匹单抗用于晚期黑色素瘤。
N Engl J Med. 2015 Jun 25;372(26):2521-32. doi: 10.1056/NEJMoa1503093. Epub 2015 Apr 19.
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Integrated NY-ESO-1 antibody and CD8+ T-cell responses correlate with clinical benefit in advanced melanoma patients treated with ipilimumab.在接受伊匹单抗治疗的晚期黑色素瘤患者中，NY-ESO-1 抗体和 CD8+ T 细胞反应的综合与临床获益相关。
Proc Natl Acad Sci U S A. 2011 Oct 4;108(40):16723-8. doi: 10.1073/pnas.1110814108. Epub 2011 Sep 20.