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中药治疗心律失常的有效性和安全性:随机对照试验的Meta分析

Efficacy and Safety of Chinese Medicine in Treating Arrhythmia: Meta-Analysis of Randomized Controlled Trials.

作者信息

He Hanyu, Han Guoning, Li Xinju, Lan Hongyi, Li Ying, Dou Xiaoxin, Guo Yi, Zhang Mingxing, Liu Hongyan

机构信息

School of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.

School of Acupuncture & Moxibustion and Tuina, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.

出版信息

Evid Based Complement Alternat Med. 2021 Oct 29;2021:9960471. doi: 10.1155/2021/9960471. eCollection 2021.

Abstract

OBJECTIVE

To evaluate the clinical efficacy of traditional Chinese medicine in the treatment of arrhythmia.

METHODS

The researchers searched CNKI, VIP, WF, PubMed, Web of Science, and Cochrane Library with the set-up themes as randomized controlled trials (RCTs) on the clinical efficacy of traditional Chinese medicine in the treatment of arrhythmia. This research evaluated all the retrieve literature and conducted selection based on the evaluation. Stata software was applied for meta-analysis.

RESULTS

23 articles were retrieved with a total patient number of 2846. The results observed from the meta-analysis indicated the following: (1) compared with the result showed in placebo group, the traditional Chinese medicine group presented to have good efficacy, especially in the treatment of premature ventricular contractions. (2) In comparison with the western medicine group, the curative effect of Chinese medicine could approximately equal the therapeutic effect as western medicine. (3) Compared with the application of sole western medicine group, the combination of both traditional Chinese medicine and western medicine could have a better curative effect.

CONCLUSION

In the treatment of arrhythmia disease, the application of traditional Chinese medicine can be considered as an effective method. In addition to that, the therapeutic effect obtained from the combination of both Chinese traditional medicine and western medicine is clinically better than that of the sole use of western medicine.

摘要

目的

评估中药治疗心律失常的临床疗效。

方法

研究人员以中药治疗心律失常临床疗效的随机对照试验(RCTs)为设定主题,检索中国知网(CNKI)、维普资讯(VIP)、万方数据(WF)、美国国立医学图书馆生物医学信息检索系统(PubMed)、科学网(Web of Science)和考克兰图书馆。本研究对所有检索到的文献进行评估,并基于评估进行筛选。应用Stata软件进行荟萃分析。

结果

共检索到23篇文章,患者总数为2846例。荟萃分析结果表明:(1)与安慰剂组相比,中药组疗效良好,尤其在治疗室性早搏方面。(2)与西药组相比,中药的疗效与西药大致相当。(3)与单纯西药组相比,中药与西药联合应用疗效更佳。

结论

在心律失常疾病的治疗中,中药的应用可被视为一种有效方法。此外,中西医结合的治疗效果在临床上优于单纯使用西药。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c4b/8570860/55d29fd3011e/ECAM2021-9960471.001.jpg

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