First Department of Health Care, The Second Medical Center and National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing 100853, China.
Department of Disease Control and Prevention, The First Medical Center of Chinese PLA General Hospital, Beijing 100853, China.
J Healthc Eng. 2021 Oct 27;2021:1535046. doi: 10.1155/2021/1535046. eCollection 2021.
This research aimed to explore the application of a mathematical model based on deep learning in hospital infection control of novel coronavirus (COVID-19) pneumonia.
First, the epidemic data of Beijing, China, were utilized to make a definite susceptible-infected-removed (SIR) model fitting to determine the estimated value of the COVID-19 removal intensity , which was then used to do a determined SIR model and a stochastic SIR model fitting for the hospital. In addition, the reasonable and estimates of the hospital were determined, and the spread of the epidemic in hospital was simulated, to discuss the impact of basal reproductive number changes, isolation, vaccination, and so forth on COVID-19.
There was a certain gap between the fitting of SIR to the remover and the actual data. The fitting of the number of infections was accurate. The growth rate of the number of infections decreased after measures, such as isolation, were taken. The effect of herd immunity was achieved after the overall immunity reached 70.9%.
The SIR model based on deep learning and the stochastic SIR fitting model were accurate in judging the development trend of the epidemic, which can provide basis and reference for hospital epidemic infection control.
本研究旨在探讨基于深度学习的数学模型在新型冠状病毒(COVID-19)肺炎医院感染控制中的应用。
首先,利用中国北京的疫情数据,建立一个确定的易感-感染-清除(SIR)模型进行拟合,以确定 COVID-19 清除强度的估计值,然后对医院进行确定的 SIR 模型和随机 SIR 模型拟合。此外,确定医院的合理和估计值,并模拟疫情在医院的传播,以讨论基本繁殖数变化、隔离、疫苗接种等对 COVID-19 的影响。
SIR 对清除者的拟合与实际数据之间存在一定差距。感染人数的拟合是准确的。采取隔离等措施后,感染人数的增长率下降。当整体免疫力达到 70.9%时,实现了群体免疫效应。
基于深度学习的 SIR 模型和随机 SIR 拟合模型准确判断了疫情的发展趋势,可为医院疫情感染控制提供依据和参考。